INSIGHTS ON MANUFACTURING LOGISTICS

• How To Select the Best Courier Around The Globe

  As a leading biotechnology company's pipeline and global presence continued to grow, management of the supply chain presented challenges. Additionally, cost pressures demanded a tighter supply chain with better control over inventory levels, and there was a need for increased temperature monitoring of clinical supplies in transit. Learn how data-driven decisions allowed them to realize cost & performance improvements across the supply chain.

• Early Licensure Of A Breakthrough Cancer Drug Gives Hope To Patients

  No clinical supply request could be a higher priority than that of a physician urgently seeking an investigational cancer drug for a patient who has exhausted all treatment options. Read how named patient and expanded access programs helped speed the licensure of a breakthrough cancer drug.

• Storage Density Problem Solved With Single-Use Bags

  Learn how a global biopharma overcame growing cold storage capacity expenses by moving to single-use bags with high storage density secondary packaging, purpose-built for freezing applications. 

• Liquid Retention Comparison In PC And PETG Containers

  Fluid retention is an important consideration when choosing a container. The physical design and material of construction of the container impact how much fluid remains after dispensing. Fluid retention is an important consideration when choosing which container to use. This application note is a comparison between different container products.

• Key Considerations For Labeling Your Cell Or Gene Therapy

  As sponsors focus on maintaining the temperature range required for cell and gene therapies, they must also keep in mind the challenges this task presents when properly labeling them for clinical trial distribution.

• Transportation Solutions For Cell And Gene Therapy Supply Chains

  Developing a strong supply chain for your cell and gene therapy can make your company a more attractive target for acquisition as well as a more competitive player in the commercial environment.

• Challenges In Bulk Drug Substance Logistics – Overcoming The Hurdles

  Freezing of biotherapeutics is a common unit operation, primarily used to extend the shelf life of the drug substance and provide flexibility in production and logistics. While technically simple to perform, the freeze-storage-thaw cycle comprises several mechanistic aspects that can compromise protein quality if not properly understood and addressed.

• Bulk Drug Substance Logistics – Primary Packaging

  There are currently many options of primary packages on how to transport the drug substance from A to B. This paper explains the benefits and shortcomings of a few of those options.

• How To Avoid Bag Breakages With Product Loss

  A global CMO producing high-value mAbs in batch sizes from 10l to 700l faced the challenge of high loss rates with single use bags at sub-zero temperatures. Here's how they solved it.