06.24.24 -- Balanced Sourcing Of Custom Media/Buffer Formulations, Part 2: The Case For Insourcing

Review the advantages and limitations of transcriptional assays versus reporter gene assays and how the transcriptional assay compares to ddPCR and flow cytometry for analysis of CGTs.

To ensure patient safety — as well as a portable process outside of Europe — it’s time to find a novel reagent without harmful, endocrine-disrupting properties.

Here, we describe a new microbioreactor system that provides single-use, perfusion bioreactors that can replicate bench-scale perfusion processes at industrially relevant cell densities.

A high-density N-1 seed culture can improve your fed-batch process by allowing you to seed the production (N) bioreactor at a higher starting density or to replace a large N-1 bioreactor.

Build a reliable, de-risked path to the clinic while avoiding unforeseen costs and compliance-related delays with advice from Suparna Sanyal, Ph.D., Head of Viral Vectors Commercial Development.

Customizing cell culture media is an important part of the early stages of development considering its composition is crucial for cellular therapeutics' success

Modeling and simulation can be a powerful tool for bioprocess design. Find out how you can utilize an open source implementation for in silico simulation of CHO.

This article explores the use of viral vectors in gene therapies, as well as factors that negatively affect them during manufacturing.

Currently, no licensed vaccine is available to prevent shigellosis. Explore the results of a study of IpaB expression optimization and scale up.

The FDA holds strict requirements for magnetic bead removal prior to therapeutic use. Learn how this system effectively separates cells from microcarriers and provides maximum cell recovery.

Gain insights into the latest advancements in high-resolution multi-plane whole well imaging and the impact of AI-powered image analysis on clonality decisions and optimal clone selection.

In this assessment of the in vitro glycoengineering technology we determine if it is suitable for the development, manufacturing, and analysis of therapeutic proteins.