Featured Articles
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Column Packing Protocol For Amsphere A3
This packing protocol is for small columns (1-20 mL, ID=0.5-1 cm). Recommended packing method is by flow.
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Minimize Compromise On Selecting A Protein A Resin For Bioprocessing
Protein A affinity chromatography represents the key initial capture method in mAb purification. There are three major types of protein A “resin” based on a different matrix chemistries.
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Viral Contaminant Removal By Protein A Resin
Protein A chromatography is capable of reducing the amounts of viral contaminants and can be utilized in downstream purification to support viral clearance for GMP manufacturing.
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Optimization Of Protein A Chromatography Process For A Herceptin Biosimilar
Four Protein A resins, including AmsphereTM A3, were screened for use in a capture step for a Herceptin biosimilar. Multiple parameters were assessed for their performance against the platform resin.
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Purification Performance Of Amsphere A3 And Other Protein A Resins
Recent results using new Amsphere A3 versus Polymer H and Agarose show that the Amsphere A3 design minimizes compromise in protein A resin performance criteria.
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Optimization Of Protein A Chromatography For Trastuzumab
Four Protein A resins were screened for use in a capture step for a Herceptin biosimilar. Multiple parameters were assessed for their performance against the platform resin.
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Fc-fusion Purification Performance: Amsphere A3 Vs. Other Protein A Resins
The DBC and purification of Fc-fusion and bispecific Ab proteins are compared on A3 and other commercial Protein A resins, with a discussion of the molecular basis for A3’s high affinity for target molecules.
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Host Cell Protein Clearance By Amsphere A3 And Other Protein A Resins
Clearance of HCPs is one of the performance parameters of downstream antibody production. In this poster, results for Amsphere A3 were compared with two other commercially available resins.