Insights On Upstream Manufacturing

  1. The Growing Role Of MSCs In Regenerative Medicine 9/10/2025

    Mesenchymal stem cells (MSCs) show great promise in regenerative medicine, but scaling their production for clinical use is a key challenge that requires careful optimization and planning.

  2. The Hidden Cost Of Off-The-Shelf Media In Cell Therapy 9/10/2025

    Generic, off-the-shelf media can introduce hidden costs and delays in cell and gene therapy development. A strategic media approach is a critical advantage that can accelerate your path to the clinic.

  3. CDMO Hunger Games And The State Of Biotech With Siren Biotechnology's Nicole Paulk, Ph.D. 9/9/2025

    Biotech leader Nicole Paulk, Ph.D., joins “Better Biopharma” to discuss Siren Biotechnology’s switch from plasmids to producer cell lines, CGT funding challenges, and the competition that determined which CDMO won Siren’s business.

  4. Cell Culture Media Fingerprinting 9/8/2025

    Ensure consistency and quality in production with an advanced CCM fingerprinting technique that is capable of identifying over 100 media components to reduce variability and meet regulatory standards.

  5. How To Fingerprint Cell Culture Media 9/8/2025

    Ensuring media identity and consistency is vital in biologics manufacturing. Discover why quantifying cell culture media components before batch release helps overcome formulation complexity.

  6. Take A Virtual Tour Of Our Cell Line Development Centre Of Excellence 9/8/2025

    Explore the advanced capabilities of our Cell Line Development Center in Ulm, Germany. From expert teams to streamlined processes, discover how we support biopharma innovation.

  7. Progressing A Cystic Fibrosis Treatment With A Strong Culture Match 9/4/2025

    Collaborate with an experienced CMO that combines transparency, expertise, and a shared commitment to help advance complex biologics from preclinical research to clinical success.

  8. Cell Cycle Mapping In Tumors With Advanced Technologies 9/2/2025

    Discover how spatial profiling and advanced imaging tools are transforming drug discovery, featuring Wayne Stallaert’s lab’s work on cell cycle mapping and biomarker insights in cancer research.

  9. Is Your Current AAV Process Holding You Back? 9/2/2025

    A novel stabilization method extends transfection complex viability from minutes to hours, providing critical flexibility and de-risking the process for more predictable and efficient workflows.

  10. PEI And Non-PEI Transfection Solutions For High Titers And Production 9/2/2025

    Discover optimized AAV production with polyethylenimine (PEI) and non-polyethylenimine transfection solutions that are designed to boost titers and streamline scalability.