Downstream Processing Featured Articles

  1. Genzyme Pioneering Continuous Manufacturing In Biotech 6/16/2015

    One company that has made significant progress in the development of a continuous manufacturing platform for large molecule drugs is Genzyme. I recently spoke with Jason Walther, a staff scientist at Genzyme, about the impact of continuous manufacturing on the industry as well as its potential. 

  2. Ultrasound Idea: Prototype NIST/CU Bioreactor Evaluates Engineered Tissue While Creating It 5/2/2012

    Researchers at the National Institute of Standards and Technology (NIST) have developed a prototype bioreactor—a device for culturing cells to create engineered tissues—that both stimulates and evaluates tissue as it grows, mimicking natural processes while eliminating the need to stop periodically to cut up samples for analysis.

  3. Ablynx's Anti-IL-6R Nanobody, ALX-0061, Shows Excellent 24 Week Safety And Efficacy Results In A Phase II Clinical Trial In Rheumatoid Arthritis 2/13/2013

    Ablynx (EURONEXT BRUSSELS: ABLX) today announced efficacy and safety data for its anti-IL-6R Nanobody, ALX-0061, at the 24 week final analysis of the Phase II part of a combined Phase I/II study in patients with moderately to severely active rheumatoid arthritis (RA) on a stable background of methotrexate.

  4. High-Flow Sterile Connectors For Single-Use Applications

    Over the past decade, two developments have increased demand for high fl ow-rate connectors: Size advances in single-use bioreactors up to 2000L and the  implementation of single-use downstream.

  5. New CU-Boulder Discoveries Hold Promise For Treatment Of Hepatitis B Virus Infection 10/22/2012

    A University of Colorado Boulder-led team has discovered two prime targets of the Hepatitis B virus in liver cells, findings that could lead to treatment of liver disease in some of the 400 million people worldwide currently infected with the virus.

  6. Automation To Solve Sample Lysis Bottleneck For Molecular Biology Labs 11/20/2012

    Hamilton Robotics is launching the Microlab AutoLys STAR workstation, which automates sample lysis and DNA extraction. This innovative instrument improves bottlenecks for forensic scientists and other molecular biologists isolating nucleic acids from samples.

  7. New Epoch 2 Provides Enhanced User Interface For Spectral Absorbance Detection 7/2/2014

    BioTek proudly unveils the new Epoch™ 2 Microplate Spectrophotometer. Epoch 2 is the first reader to combine a large touchscreen and full onboard data analysis software for simplified and efficient operation and reporting of absorbance-based detection workflows.

  8. AET BioTech And BioXpress Therapeutics To Co-Develop Biosimilar Adalimumab 10/30/2012

    AET BioTech, the separate biosimilars business within the generic drug developer AET (Alfred E Tiefenbacher) Group and BioXpress Therapeutics SA, a Swiss-based biotechnology company developing monoclonal antibody (MAb) biosimilars have entered into an agreement for the co-development of a biosimilar version of the TNF inhibitor MAb Adalimumab.

  9. Phenex Enters Into A Research Collaboration And License Agreement With Janssen For Autoimmune And Chronic Inflammatory Disorders 12/17/2012

    Phenex Pharmaceuticals AG (Phenex) today announced it has entered into an agreement with Janssen Biotech, Inc. and its affiliates (Janssen) to jointly discover compounds that target the nuclear hormone receptor RORγT and may have utility in the treatment of chronic autoimmune and inflammatory disorders including rheumatoid arthritis, psoriasis, and inflammatory bowel disease.

  10. Putting Capillary Electrophoresis to Work 3/8/1999
    It's been over 10 years since the first commercial instrument for capillary electrophoresis (CE) was introduced with a fanfare and a list of promises to revolutionize the world of separation science...