Synergies For Equipping The Single-Use Bioproduction Suite

The growth of biopharmaceuticals entering the market has served to change the appearance of the bioproduction suite. For certain biopharmaceutical products, large-scale equipment such as stainless steel reactors, tanks, and piping are being replaced in many settings with plastic fluid containment, cell culture ware, and fluid transfer products. The economic and regulatory advantages of single-use components are well documented.

The introduction of new and innovative single-use products continues apace, giving biopharmaceutical manufacturers attractive alternatives for product selection. Choices are based not only on the end products and processes involved, but also regulatory requirements and maintenance. Because use of disposable products on commercial manufacturing scale is an emerging field, it would be ideal to work with a portfolio-rich manufacturer using a consultative approach.

As one of the world's leading manufacturers of plastic biotechnology products, Nalge Nunc International offers the ability to employ synergies in the combination of its two well known brand names, NALGENE® and NUNC™. Nalge Nunc International offers a fully integrated product portfolio supported by expert technical assistance for bioproduction applications.

• Fluid Containment products, including carboys, tanks, bags, tank liners, polyethylene terephthalate (PET) and polyethylene terephthalate copolymer (PETG) media bottles are used to formulate and contain media or feed stock solutions.
  
• Fluid transfer products include customized fluid transfer tubing sets, a standard offering of TopWorks™ closure systems, as well as extensive tubing offering available in a variety of materials including silicone, polyvinyl chloride (PVC), polyurethane (PUR), Teflon FEP (fluorinated ethylene propylene), and Teflon PFA (perfluoroalkoxy).
  
• Cell culture platforms include Cell Factories, roller bottles, shaker flasks, culture vessels, and microcarriers.
  
• Other key products with applications in the bioproduction suite include centrifuge bottles, cryovials, and bottles.

MORE THAN PRODUCTS: A SOLUTION PROVIDER APPROACH

The technical support specialists at Nalge Nunc International offer the combined expertise of an experienced and well known manufacturer of plastic biotechnology products. Our knowledge in disposable technology enables not only precise material selection and use, but advanced surface modification capabilities. Our manufacturing facilities are FDA registered, and we routinely supply products for stringent, regulated applications. Upon request we provide validation binders for key products to assist our customers in supporting their quality and regulatory documentation needs. Our ability to recommend and support application-specific combinations and customized product solutions will meet your goals throughout the manufacturing lifecycle of your product in a safe, economical, and highly efficient manner.

Benefits available from the disposable technology solutions provided by from Nalge Nunc International include:

• Low initial investment costs
  
• Reduced lifetime operating costs
  
• Reduced validation complexity
  
• Reduced risk of contamination
  
• Linear scale up to larger production volumes
  
• Increased speed to market.

Nalge Nunc International will be exhibiting at upcoming industry events such as BioProcess International (San Francisco, CA - Booth 801 and 803 - November 6-9). We will be unveiling a number of new products including a rigid support system designed to optimize the management and transportation of bioprocess bags. Additionally, we will be providing a demonstration of our forthcoming on-line configuration system that will facilitate the design, product integration and order process for custom tubing sets.

In addition to supplying a complete range of bioproduction concepts, we have a dedicated team of specialists ready to assist you with development of new bioproduction methods, validation, and optimization of existing processes, as well as complete after-sales service and technical support.

SOURCE: Nalge Nunc International