Downstream Processing Featured Articles

  1. Article: How To Choose An Industrial Cation Exchanger For IgG Purification

    Cation-exchange chromatography is the third most used industrial method for antibody purification after anion-exchange and protein A affinity chromatography. It is most commonly used as an intermediate step but continues to attract attention as a capture method. By Pete Gagnon

  2. Stainless Steel Vial Filling System Developed For Use In Vaccine Facilities 7/17/2014

    TAP Biosystems (now part of the Sartorius Stedim Biotech Group), a leading supplier of innovative cell culture and fermentation systems for life science applications, recently announced the development of a stainless steel version of the fill-it system, designed for safely dispensing biohazardous materials such as vaccine stocks.

  3. BARDA Continues Novavax' Influenza Vaccine Programs Following In-Process Review 1/24/2013

    Novavax, Inc. (Nasdaq:NVAX) today announced that the U.S. Department of Health and Human Services, Biomedical Advanced Research and Development Authority (BARDA) has completed an In-Process Review (IPR) of Novavax' contract covering the company's recombinant virus-like particle (VLP) vaccine candidates for pandemic and seasonal influenza.

  4. Frost & Sullivan Lauds Pfenex Inc. For Developing A Protein Expression Platform That Delivers Unparalleled Success And Speed 6/5/2012

    Based on its comprehensive  TEAM Research rigorous 10 step evaluation methodology, Frost & Sullivan has awarded Pfenex Inc. with the 2012 North American Enabling Technology Award in Microbial Expression Technology.

  5. New Look At Multitalented Protein Sheds Light On Mysteries Of HIV 11/12/2012

    New insights into the human immunodeficiency virus (HIV) infection process, which leads to acquired immunodeficiency syndrome (AIDS), may now be possible through a research method recently developed in part at the National Institute of Standards and Technology (NIST), where scientists have glimpsed an important protein molecule's behavior with unprecedented clarity.

  6. Reconstruction Of Prehistoric DNA Refutes Criticism On Theory Of Evolution 12/10/2012

    Scientists from VIB, KU Leuven, UGent and Harvard have succeeded in reconstructing DNA and proteins from prehistoric yeast cells. This made it possible to determine how genes developed and evolved into their current form over more than 100 million years.

  7. Avid Bioservices Announces Completion Of Facility Upgrades In Response To Increased Demand For Its Contract Manufacturing Services 12/13/2012

    Avid Bioservices, Inc, a contract manufacturing organization (CMO) focused on the process development and manufacturing of monoclonal antibodies, proteins and enzymes, today announced that its demand for services has reached an all-time high, while projected revenue for its current fiscal year ending April 2013 is expected to surpass $18 million, a 20% increase from the previous fiscal year.

  8. Forsyth Scientists Define The Bacteria That Live In The Mouth, Throat, And Gut 9/20/2012

    For the first time, scientists have defined the bacteria that inhabit multiple sites along the healthy human digestive tract in a large number of individuals. To prevent and control bacterial diseases, it is essential to first identify which bacteria are responsible for keeping us in good health.

  9. 3M Purification Inc. Introduces New Zeta Plus Encapsulated, Single-Use Depth Filtration Products 5/4/2012

    3M Purification Inc. has expanded its portfolio of Encapsulated Zeta Plus single-use depth filtration capsules.  The two new product lines – Zeta Plus Scale-up Capsule Filters and new single-layer media grades for Zeta Plus Encapsulated capsules – are designed with our industry leading Zeta Plus depth filter media, designed for applications in the bio-pharmaceutical industry including cell culture clarification, downstream process protection, virus, DNA and lipid reduction, and host cell protein (HCP), protein aggregate, endotoxin and anti-foaming agent removal.

  10. BioChip May Make Diagnosis Of Leukemia And HIV Faster, Cheaper 5/30/2012

    Inexpensive, portable devices that can rapidly screen cells for leukemia or HIV may soon be possible thanks to a chip that can produce three-dimensional focusing of a stream of cells, according to researchers.