Downstream Processing Featured Articles

41. Cancer Cell Article Demonstrates First Definitive Evidence For Targeting of Pol I As New Approach To Cancer Therapy 7/10/2012

    Cylene Pharmaceuticals today announced that research collaborators at the Peter MacCallum Cancer Centre (Peter Mac) in Melbourne, Australia have established, for the first time, that RNA Polymerase I (Pol I) activity is essential for cancer cell survival and that its inhibition selectively activates p53 to kill tumors.

     

42. Lpath Receives First U.S. Patent For Anti-LPA Antibody, Lpathomab 4/25/2012

    Lpath, Inc. (OTCBB: LPTN), the industry leader in lipidomics-based therapeutics, received official notification from the U.S. Patent and Trademark Office (USPTO) that it has been issued a key patent protecting Lpathomab™, a monoclonal antibody against lysophosphatidic acid (LPA).

43. Genetic Immunity Receives GMP Certification For In-House Manufacturing Facility 10/8/2012

    Genetic Immunity (OTCBB: PWRV) is pleased to announce the GMP approval of its manufacturing facility. The development of the GMP manufacturing process and the facility was financed from a $4 million grant received from the Hungarian Office for Innovation and Technology.

44. Newfound Gene May Help Bacteria Survive In Extreme Environments 7/25/2012

    In the days following the 2010 Deepwater Horizon oil spill, methane-eating bacteria bloomed in the Gulf of Mexico, feasting on the methane that gushed, along with oil, from the damaged well. The sudden influx of microbes was a scientific curiosity: Prior to the oil spill, scientists had observed relatively few signs of methane-eating microbes in the area. By Jennifer Chu, MIT

45. Scientists Show Protein-Making Machinery Can Switch Gears With A Small Structural Change 11/15/2012

    For the past several years, Min Guo, an assistant professor at The Scripps Research Institute (TSRI), has focused on the intricate actions of an ancient family of catalytic enzymes that play a key role in translation, the process of producing proteins.

46. Roche And BioLamina Start Collaboration To Develop Novel Cell Culture Systems 3/6/2013

    BioLamina, Stockholm, Sweden and Roche recently announced the signing of a research and development agreement to jointly develop new cell culture systems for various applications, including stem cell research.

47. Researchers Develop Method To Grow Artificial Tissues With Embedded Nanoscale sensors 8/26/2012

    A multi-institutional research team has developed a method for embedding networks of biocompatible nanoscale wires within engineered tissues. These networks—which mark the first time that electronics and tissue have been truly merged in 3D—allow direct tissue sensing and potentially stimulation, a potential boon for development of engineered tissues that incorporate capabilities for monitoring and stimulation, and of devices for screening new drugs.

48. Protein Central To Cancer Stem Cell Formation Provides New Potential Target 2/13/2013

    Researchers have identified a pivotal protein in a cellular transformation that makes a cancer cell more resistant to treatment and more capable of growing and spreading, making it an inviting new target for drug development.

49. Standardized Extractables Testing Advances Single Use Adoption 6/3/2015

    The Standardized Extractables Testing Protocol For Single-Use Systems In Biomanufacturing written by BPOG members last year establishes a foundation from which to create a standardized approach to extractables testing. However, since its release, there have been some questions and discussions about how to effectively implement the protocol.

50. New Cell Type Developed For Possible Treatment Of Alzheimer's And Other Brain Diseases 11/7/2012

    UC Irvine researchers have created a new stem cell-derived cell type with unique promise for treating neurodegenerative diseases such as Alzheimer’s.