Downstream Processing Featured Articles
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PBS Biotech Launches Single-Use Bioreactor For Development Of New Vaccines And Biosimilars
5/25/2011
PBS Biotech, Inc., a developer of state of the art bioreactors to be used in the fast growing biotechnology market, announced recently the launch of its innovative PBS 3 single-use bioreactor system.
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New Hope For Understanding Autism Spectrum Disorders
11/21/2012
Researchers from McGill University and the University of Montreal have identified a crucial link between protein synthesis and autism spectrum disorders (ASD), which can bolster new therapeutic avenues. Regulation of protein synthesis, also termed mRNA translation, is the process by which cells manufacture proteins.
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New Insights Into HIV Vaccine Protection Will Improve Drug Development
1/28/2013
Four years ago, a potential HIV vaccine showed promise against the virus that causes AIDS, but it fell short of providing the broad protection necessary to stem the spread of disease.
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Engineered Tissue Vary Depending On Where It's Grown
8/16/2012
MIT researchers led by Elazer Edelman, the Thomas D. and Virginia W. Cabot Professor of Health Sciences and Technology, have now shown that implanted cells’ therapeutic properties depend on their shape, which is determined by the type of scaffold on which they are grown.
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Article: How To Choose An Industrial Cation Exchanger For IgG Purification
Cation-exchange chromatography is the third most used industrial method for antibody purification after anion-exchange and protein A affinity chromatography. It is most commonly used as an intermediate step but continues to attract attention as a capture method. By Pete Gagnon
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Pathobiology Professor's Vaccine Platform Gives Immune Systems A Boost
11/28/2012
Dr. Bernhard Kaltenboeck, professor of pathobiology in Auburn University’s College of Veterinary Medicine, and research associates Erfan Chowdhury and Yihang Li have developed a vaccine platform to treat intracellular diseases for which antibodies are ineffective.
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Crucell And Scripps Research Discover And Describe Broad-Spectrum Antibodies Against Influenza B, A Crucial Link In Development Of Universal Flu Therapies And Vaccine
8/9/2012
In a landmark discovery, researchers from Crucell Holland B.V. and The Scripps Research Institute, recently announced the identification of the first human monoclonal antibodies that appear capable of disabling all influenza B viruses.
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Damania Lab Discovers Gene That Suppresses Herpesviruses
2/14/2013
In a paper published by Cell Host and Microbe on Feb. 13, a research team led by Blossom Damania, PhD, of the Department of Microbiology and Immunology and member of the UNC Lineberger Comprehensive Cancer Center, found that suppressing the TLK enzyme causes the activation of the lytic cycle of both EBV and KSHV. During this active phase, these viruses begin to spread and replicate, and become vulnerable to anti-viral treatments.
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New Monoclonal Antibody Developed That Can Target Proteins Inside Cancer Cells
3/13/2013
Researchers have discovered a unique monoclonal antibody that can effectively reach inside a cancer cell, a key goal for these important anticancer agents, since most proteins that cause cancer or are associated with cancer are buried inside cancer cells.
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FlexFill Single-Use Transfer Assembly
10/3/2011
Meissner introduces its new FlexFill single-use biocontainer transfer assembly. The assembly is ideally suited for applications requiring fast and dependable aseptic transfer of small liquid process volumes.