Purifying Infectious Virus Particles Using ÄKTA™ Start

Viruses are extensively used as therapeutic agents and molecular and cellular biology tools. Several uses have been found for these unique organisms in medicine and genetic engineering, including use as research as tools in gene manipulation and the investigation of cellular functions. Easily and efficiently purifying virus particles will accelerate virology developments.

This application note demonstrates a chromatography method for the purification of reovirus RNA virus particles using a small benchtop chromatography system, ÄKTA start, and HiTrap Capto Core 700 1 mL column.