Culture Development White Papers and Case Studies
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White Paper: CA19-9 Antigen
6/26/2007
CA19-9 is a monoclonal antibody generated against a colon carcinoma cell line to detect a monosialoganglioside found in patients with gastrointestinal adenocarcinoma
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White Paper On Ca-125 Ovarian Tumor Antigen
3/29/2007
Bioprocessing, Inc. President Gary Goodrich shares his knowledge of biomarker assay reagents gathered through 16 years of experience in the manufacture of tumor marker glycoproteins
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The Case For Integrated Processes
3/28/2007
Based on research and documented case studies, it is clear that companies are realizing significant value by developing integrated processes across the enterprise. This white paper discusses what integrated processes are, how they create value, specific cases of companies succeeding with integrated processes, as well as a checklist to determine how integrated your own company’s processes are. Submitted by SAP Americas
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The Case For Integrated Processes
8/14/2006
Whitepaper: The Case For Integrated Processes
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Improving DNA Removal from Bioprocess Purification Processes
Many new biological drug products produced using recombinant DNA technology, such as monoclonal antibodies, are produced in cell culture. Because therapeutic proteins such as monoclonal antibodies are produced in cell culture, impurities can result from the host cells, or cell substrates. By 3M Purification Inc.
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Removal Of Host Cell Proteins During Monoclonal Antibody Purification
Protein A chromatography is a widely used and highly successful method of purifying recombinant monoclonal antibodies. However, since Protein A has high affinity for antibodies, harsh conditions such as low pH are often required to elute monoclonal antibodies from Protein A affinity columns. By 3M Purification Inc
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Rapid Chemically-Defined Feed Media Development to Improve Simulated Cell Culture Processes
Implementing an optimized feed medium may be the most effective alternative for modifications to the growth medium in an existing process.
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Comparison Of Five Cell Culture Media Demonstrating CHO Cell Culture Growth In Batch Or Fed-Batch Process For Commercial Operations
This case study details a two month, four phase project to design chemically-defined feed media that improved two simulated batch processes utilizing products by SAFC, Life Technologies, Thermo Fisher Scientific, and Irvine Scientific. By Mark C. Arjona, Evan R. Horowitz, Alex A. Jurisch, Jenny Y. Bang, Tom Fletcher, Irvine Scientific
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The Next Generation Drug Delivery Devices
An exciting trend in drug delivery is the movement toward smaller, smarter, wirelessly connected electronic devices that allow patient-administered therapy. Inspired by technological advancements driving the consumer electronics market, new drug-delivery methods show promise for all stakeholders.
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Applications And Integration Of Hydrogen Peroxide Vapor For Biotech/Bioprocess
The increase in size and scale of bio-processing is presenting a new challenge. Traditional methods of sterilisation, to maintain clean facilities, are becoming difficult to deploy in a controlled and regulatory compliant way. By Richard Lucas, Ph.D., Bioquell UK Ltd.