Bioprocessing White Papers

  1. Cryopreservation Of Cells: Preserving Cells For Future Use 9/11/2023

    Take a closer look at the process of cryopreservation, which role it plays for cell banking, and which challenges have to be overcome to reach the successful cryopreservation of cells.

  2. Can Yeast Be The Future Of Efficient Subunit Vaccine Manufacturing? 9/11/2023

    To aid in the manufacturing of new vaccines, Pichia pastoris yeast, a promising protein expression system, could be the perfect solution.

  3. Purity Analysis Methods For Synthetic Prime Editing Guide RNAs 9/8/2023

    Develop a fast, easy workflow for the purity analysis of complex pegRNA molecules along with a robust denaturing technique for pegRNA with high levels of secondary structure.

  4. Add A 3rd Dimension To Your Immunoassay 9/7/2023

    If you are seeking protein size separation information in addition to immunodetection of protein target(s) of interest, these assay can more provide sensitive, accurate, and reproducible read-outs than ELISA.

  5. Guide To Seeding, Expanding, And Harvesting Stem Cells 9/5/2023

    Investigate important considerations for working with three different stem cell types: mesenchymal stem/stromal cells, induced pluripotent stem cells, and neural stem cells.

  6. Single-Use vs. Stainless Steel Debate In Biopharmaceutical Manufacturing 9/1/2023

    Investigate the advantages and disadvantages of single-use technologies and stainless steel systems with a focus on performance, adaptability, and economics.

  7. Comparing Single-Use To Fixed Bioprocessing Systems 9/1/2023

    Several life cycle assessments have been conducted comparing the environmental impact of SUTs to conventional fixed systems, leading to results that could inform changes in bioprocess system use.

  8. Sterile Filtration And Quality Risk Management 8/31/2023

    Process control is essential for manufacturing sterile products. Explore the role of filtration for bioburden control in quality risk management and contamination control strategies.

  9. Eliminating USP <88> In Vivo Animal Bioreactivity Testing For Polymer Characterization 8/25/2023

    There has been growing awareness about the environmental and ethical implications of plastics used in bioprocessing. The time for a shift to well-studied, proven in vitro cytotoxicity testing is now.

  10. Recommendations For Successful IND Approval Of RNA-LNP Drugs 8/22/2023

    The existing regulatory system is ambiguous for RNA therapeutics. Leverage this Investigational New Drug (IND) guide to help accelerate and strengthen the process IND filing of novel nanomedicines.