Bioprocessing White Papers

  1. Bringing The Freezing Of Biopharmaceuticals In From The Cold 3/18/2021

    In this paper, we review end-to-end freezing solutions that integrate bulk filling, storage, shipping, thawing, and fill-finish operations to minimize risk and preserve product quality.

  2. Producing Publication-Quality Data With Automated Western Blots 3/16/2021

    How Simple Western overcomes the challenges and pitfalls associated with traditional Western blots to produce publication-ready data that meets the highest standards of data integrity and rigor.

  3. Navigating The Adoption Of Continuous Pharma Manufacturing 3/1/2021

    Driving a path forward for continuous manufacturing calls for a closer look at current global challenges, any existing barriers, and the ideas and initiatives necessary to fulfill its potential.

  4. Nanoparticles Drive The Nanotechnology Revolution 2/26/2021

    Nanotechnology has been referred to as potentially being the next technical revolution that could change the modern world. Perhaps the developments seen to date do not yet match this build up, but the combined investment by governments, universities, and industry is significant with global government investment exceeding $9 billion annually and growing. The United States government alone has invested over $27 billion since from 2001 – 2019.2 The global nanotechnology market has been estimated to be between $10 – 50 billion annually depending on definitions and sources.

  5. Intensified Buffer Management For Manufacturing Efficiency, Reduced Cost 2/26/2021

    This white paper describes a novel, integrated approach to intensified buffer preparation and how this strategy can increase process flexibility, efficiency and reduce costs.

  6. Accelerate CHO Cell Characterization With The Blazar™ Rodent Panel: A Guide For Adoption 2/24/2021

    The development of the Blazar™ Rodent Panel allows biopharma to move away from traditional in vivo antibody production assays when characterizing cell banks of rodent origin used in the production of biologicals.

  7. Freezing & Storing Biopharmaceuticals At -80° C And Below 2/24/2021

    There are many choices for freezing biopharmaceutical bulk material. This paper demonstrates that the initial price can be deceiving and the significant additional costs during ongoing usage. 

  8. Manufacturing For Biopharma: Should I Build Or Outsource? 2/19/2021

    The standardization of biologics manufacturing processes has given product developers multiple viable options for producing monoclonal antibodies (mAbs), including building an in-house mAb production system or partnering with a contract biologics manufacturer. This article shares a success story for an early-stage technology transfer and the parameters to consider to stay ahead of your competitors.

  9. Manufacturing Strategies For mRNA Vaccines And Therapeutics 2/19/2021

    mRNA has emerged as a promising modality for a wide range of therapeutics and vaccines and could become the break-through technology of this century. This technology will not only revolutionize the field of vaccine development by allowing a rapid response to disease outbreaks, it will also help to address diseases of unmet medical need with gene therapy approaches or cancer treatments. Learn more with our white paper.

  10. FMD Virus Vaccine: Filtration Strategies Optimize Development, Purification 2/19/2021

    How a collaboration with MEVAC optimized filtration strategies used in upstream and downstream processing of a foot and mouth disease virus vaccine to ensure scalable, cost effective GMP.