Bioprocessing White Papers

31. Harnessing Amino Acid Derivatives To Improve Monoclonal Antibodies 8/20/2023

    Recent research in the fast-growing market of monoclonal antibodies (mAbs) identifies excipients that reduce viscosity of high-concentration formulation and improve stability across a wide concentration range.

32. COGs Process Economics For Autologous Cell Therapy 8/11/2023

    Analyze the cost distribution over time for autologous CAR T therapy manufacturing using process economics and insights from scientists and R&D. Discover how cell therapy manufacturers can combat these costs.

33. The State Of Plastics Recycling In BioPharma 8/9/2023

    Recycling plastics from biomanufacturing proves uniquely difficult due to circularity, quality, and infrastructure challenges. Nonetheless, change is underway. Learn how this change is being spearheaded by industry leaders.

34. Inspection Of Injectable Products For Visible Particulates 8/8/2023

    Examine the risks posed by particulates, the potential sources and types of particulates, and approaches to detect and measure visible particulates in injectables.

35. Critical Considerations For Buffer Preparation 8/7/2023

    Learn about the steps of buffer development, supply approach and strategy selection, choosing between in-house and outsourcing buffer activities, and other related buffer use topics.

36. Considerations And Strategies For Oligonucleotide Manufacturing Scale-Up 8/2/2023

     To keep up with oligonucleotide demand, manufacturing needs to shift toward larger-scale processes, but this up-scaling process brings challenges that must be addressed.

37. Characterize T Cell Exhaustion And Hypofunctionality In Cancer 7/31/2023

    Investigate what drives the hypofunctional state of T cells in ICB-nonresponsive cancers through the characterization of CD8+ T cell functionality in different tumor types. 

38. Switching From Vials To PFS And Intravenous To Subcutaneous Formulations 7/25/2023

    Learn about formulation development challenges for prefilled syringes as well as considerations for reducing the time it takes to launch safer, more convenient, and cost-effective products for the patient.

39. Solving Cost And Supply Challenges In Biopharma Downstream Processing 7/20/2023

    In response to the growing demand for monoclonal antibodies, researchers are looking at different areas of the downstream process where they can improve efficiency and scalability.

40. De-risks Your Monoclonal Antibody Scale-Up Process 7/20/2023

    Improve your mAb production by adopting a technology platform approach using a fluid handling system that can transition from development to your final production volume.