Bioprocessing White Papers

  1. Challenges And Solutions In Lyophilization Development For ADCs 12/10/2025

    Successful ADC lyophilization requires a robust, individualized process driven by thermal characterization using DSC and FDM to define the critical parameters for stability and efficient manufacturing.

  2. Digital Innovation And Sustainability Are Redefining Biomanufacturing 12/8/2025

    Next Generation Manufacturing (NGM) integrates advanced process design, digital innovation, and strategic facility planning to facilitate agile, efficient, and sustainable biopharmaceutical production.

  3. Comparing In-Line Vs At-Line Variable Pathlength Tech For UF/DF 11/20/2025

    Discover how rapid amino acid profiling improves media insight, detects variability, and supports real-time optimization for stronger bioprocess control, as well as strategies to reduce risk.

  4. The Proven, Practical Gateway To Upstream Process Intensification 11/18/2025

    N-1 perfusion enables higher inoculum densities, faster production, and reduced costs without altering fed-batch processes. Explore a practical path to intensification for biologics manufacturers.

  5. Rethinking Peptones As First-Line Optimization Tools 11/14/2025

    Peptones enhance CHO cell growth, viability, and yield, offering a fast, low-risk way to improve bioprocess performance without major process changes.

  6. Isolate Bright GFP-Expressing HEK293 Cells For Cell Line Development Workflow 11/7/2025

    Explore a high-efficiency workflow for isolating and expanding GFP-expressing HEK293 cells that enables stable, bright clones ideal for imaging and tracking to simplify clonal development.

  7. Generate CHO-K1 GFP-Expressing Cells For Cell Line Development Workflow 11/7/2025

    Discover a high-efficiency workflow for generating GFP-expressing CHO-K1 clones using automated single-cell dispensing to achieve 93% isolation success and stable expression in under five weeks.

  8. Build An AAV8 Platform: Lessons From A Collaborative Development Journey 11/5/2025

    Explore how a modular AAV8 platform enables scalable, GMP-ready gene therapy manufacturing with reproducible outcomes, streamlined tech transfer, and adaptability across serotypes.

  9. Excellence In Peptide And Oligonucleotide Purification 11/5/2025

    Explore how digital tools are advancing peptide purification, with a focus on GLP-1 receptor agonists, as well as how process efficiency can be accelerated through real-time insights.

  10. Tools For Efficient And Reliable Gene Therapy Manufacturing 11/5/2025

    Discover scalable strategies for overcoming AAV purification challenges, from low yield and impurity removal to serotype variability, as well as how advanced tools can streamline manufacturing.