05.26.23 -- All You Need To Know About Contamination Control Strategies, Part 1

Drug product stability may be seriously compromised if mannitol completes crystallization during storage rather than during the freezing or annealing step in the lyophilization process.

Understand high titer expression of Fc-fusion proteins using the Apollo™ X platform coupled with integrated quality assessments, enhancing support for clients through the predicted growth in Fc-fusion clinical applications.

Explore why Nano differential scanning calorimetery (DSC) is one of the best ways of measuring antibody stability with minimal sample preparation and consumption and is a possible alternative to Raman spectroscopy.

We describe a straightforward way to achieve a high-performing fed-batch process for a knockout cell line. This workflow improved titers 500% compared with CHO cell culture in basal medium.

A high-throughput formulation development for sample preparation and sample analysis enabled a simple and less labor intensive screening of a broad range of conditions in considerably less time.

Learn more about a process for the purification of BsAbs utilizing affinity chromatography followed by two polishing steps to eliminate undesirable homodimers and other impurities.

Gain a better understanding of process analytical technology (PAT), Raman spectroscopy, chemometrics, and Raman applications in bioprocessing.

Understanding how purification columns work can help operators better conceptualize the process, enabling greater process understanding and troubleshooting.

The manufacture of sterile injectables is fraught with risk, especially when it comes to protein aggregation in biologic drugs. We offer steps you can take to help prevent aggregation.

Learn about the three most common sources of filtration failures and how to prevent these problems.