Evaluating Antibody Stability With Nano Differential Scanning Calorimetry

By Nicie Murphy and Morgan Ulrich

Antibody stability is crucial for antibody performance in therapeutics. However, many antibodies, in particular monoclonal antibodies, are very costly to produce. High antibody thermostabilities are essential for creating products with a reasonable shelf life and avoiding problems with the deterioration of the biophysical properties of the antibody.

Explore why Nano differential scanning calorimetery (DSC) is one of the best ways to measure antibody stability with minimal sample preparation and consumption and a good fit when Raman spectroscopy is not appropriate for your work.