INSIGHTS ON ENTERPRISE SOLUTIONS

• Productivity Gains Upstream Apply Pressure Downstream

  In this segment from the Bioprocess Online Live event, “The Levers And Tradeoffs That Drive Process Productivity,” panelists David Scherr, Ph.D. (AstraZeneca) and Vadim Klyushnichenko, Ph.D. (Calibr-Skaggs), reflect on the progress that’s been made in terms of productivity gains and the “ceiling” that mAbs face, and how these upstream gains stress downstream operations. They also discuss how molecular complexity relates to challenges in purification.

• Continuous Manufacturing As A Powerful Productivity Lever

  In this segment from the Bioprocess Online Live event, “The Levers And Tradeoffs That Drive Process Productivity,” panelists David Scherr, Ph.D. (AstraZeneca) and Vadim Klyushnichenko, Ph.D. (Calibr-Skaggs), discuss the potential of perfusion and continuous manufacturing to improve productivity through smaller facility footprints and greater output over time. They also examine the challenges associated with these approaches, including cell-line stability, process monitoring, and the cost of operational mistakes.

• Understanding Fixed Variables And Working Within Their Constraints

  Some things are intrinsic, unchanging realities of a process — molecular complexity, product developability, and facility fit, to name a few. In this segment from the Bioprocess Online Live event, “The Levers And Tradeoffs That Drive Process Productivity,” panelists David Scherr, Ph.D. (AstraZeneca) and Vadim Klyushnichenko, Ph.D. (Calibr-Skaggs), discuss these “non-pullable levers” of process development and advise teams on how to work within their boundaries.

• Accelerating Biologics Release Testing Without Increasing Risk

  Streamline biologics release testing by balancing automated speed with regulatory compliance. High-throughput, validated workflows reduce timelines and error risks for safe, rapid, audit-ready delivery.

• Enhancing Biopharmaceutical Production Through Advanced Mixing

  6/30/2026

  Eliminate particulate contamination and product degradation in downstream bioprocessing. Learn how frictionless, levitating impeller technology ensures low-shear mixing and high yields.

• Breaking the Titer Ceiling: Smarter Media Design for Higher Productivity

  6/30/2026

  A bottom-up, data-driven media design approach shows how targeted nutrient optimization overcomes metabolic limits to boost culture performance and titer while maintaining product quality and process consistency.

• GLP-1 Oral Solid Dosage Workflow - Spray Drying And Tableting

  6/29/2026

  Optimize containment in oral GLP-1 solid dose manufacturing. Learn how closed single-use containment and flexible isolators secure blending, spray drying, and tableting workflows.

• GLP-1 OSD Chemical Synthesis Workflow

  6/29/2026

  Enhance containment and process reliability in oral GLP-1 synthesis. Discover how integrated single-use assemblies and automated fluidics safeguard chemical purity during scale-up.