Success Story: Increased Productivity With Concentrated Fed-Batch

A major biopharmaceutical company set out to develop a flexible, single-use, multi-product manufacturing facility capable of supporting a high annual production throughput exceeding 500 kilograms. To achieve this ambitious goal, the company focused on optimizing its upstream processes. After careful evaluation, they implemented a concentrated fed-batch process, which significantly enhanced productivity. This advanced approach enabled titers up to four times higher than those achieved with conventional fed-batch methods. As a result, the company not only increased its overall throughput but also gained greater flexibility in scheduling and executing production runs, which makes the facility more adaptable to varying product demands and market needs.

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