Praesto AP+50™: Process Scale Column Packing Instructions

Dive into this detailed guide for packing process-scale columns using Praesto AP+50, a high-capacity, alkaline-stable Protein A affinity chromatography resin optimized for downstream processing of monoclonal antibodies and recombinant proteins. Praesto resins, manufactured with patented Jetted Technology, offer consistent bead size, high capacity, and efficient flow properties crucial for robust and reproducible biopharmaceutical purification.

Learn about the importance of proper column packing to achieve maximum efficiency, high product yield, and purity, while mitigating costly process disruptions due to uneven flow. This guide also covers slurry determination, manual and automated packing procedures for various column types, and essential column efficiency testing methods using HETP and asymmetry factor calculations. Download these instructions to begin optimizing your bioprocessing purification.