Downstream Processing

  1. Addressing Post-Translational Modifications In Novel Protein Therapeutics 9/13/2024

    Meinhard Hasslacher, Ph.D., Head of CMC at SOTIO Biotech, addresses an audience question on conjugation efficiencies in this segment of the Bioprocess Online Live event Early Process Considerations For Novel Protein Therapeutics. From there, we move on to an audience-led discussion on when to initially address titer, PTMS, and product quality during development of novel protein therapeutic cell lines, with Lena Tholen, Ph.D, Director of Cell Line and Bioprocess Development at FyoniBio and Neeraj Pakala, Ph.D. SVP of Product Development and Manufacturing at Vera Therapeutics weighing in.

  2. Tools For Efficient Downstream Processing Of Antibody-Based Therapeutics 3/20/2025

    Watch and discover how to effectively utilize chromatography tools for improved purification of therapeutic monoclonal antibodies and antibody derivatives.

  3. Purification Tools To Address Low Yield Challenges With Protein A 5/19/2025

    Discover new affinity chromatography resins for engineered modalities. Learn how they boost yield and reduce aggregation with high-specificity binding and mild elution. Ideal for purifying novel mAbs, BsAbs, and mAb fragments.

  4. Setup Made Simple With The BioTitan Retention Device 5/27/2025

    Find out how quick and simple it is to set up an assembly secured with the Thermo Scientific BioTitan Retention Device.

  5. An Advanced Single-Use Solution for Downstream Bioprocessing 9/5/2023

    A single-use chromatography system is offering an innovative solution tailored to meet the needs of evolving downstream purification bioprocesses.

  6. Enhancing Aseptic Fill-Finish Processes 7/3/2025

    Achieve exceptional product recovery and sterility. Learn about high-integrity surge bags, advanced leak detection, and flexible design options for your fill-finish applications.

  7. Developing A 2-Step Chromatographic Process For The Purification Of AAV Vectors 6/24/2025

    POROS CaptureSelect AAVX and POROS 50 HQ were tested for capture and polishing, respectively, of AAV2, AAV9 and a novel engineered capsid to achieve vectors with high purity and significant empty: full ratio improvement.

  8. Three Novel Protein Therapeutic Worldviews 9/13/2024

    In this segment of the Bioprocess Online Live event Early Process Considerations For Novel Protein Therapeutics, we meet panelists who share their topline perspectives on developing complex, novel protein therapeutics.

  9. Simplify Your Process Of Choosing An Optimal Resin 5/19/2025

    Discover how to address evolving biotherapeutic purification challenges with a diverse resin portfolio and an intuitive Resin Selection Tool designed to streamline workflows and enhance production efficiency.

  10. What Bioprocessing Bottlenecks Does Process Intensification Address? 8/27/2024

    Supply chains, consumables, and data are identified as three of the management challenges that intensified processes and process automation technology (PAT) are addressing at AbbVie and AstraZeneca.