Downstream Processing

  1. Why AstraZeneca and AbbVie Are Intensifying Processes 8/27/2024

    In this segment of the Bioprocess Online Live event Bioprocess Intensification In The Real World, our speakers share the motivation for continued process intensification in their respective organizations.

  2. BioTitan Retention Device Overview 5/29/2025

    Learn about a retention device that provides robust fortification for single-use assemblies. Its 360-degree seal strengthens connections, reduces leak risks, and ensures process integrity for fluid transfer.

  3. Ingress Leak Test For Bioprocess Containers 5/28/2025

    When a visual inspection with magnification isn't enough, the IPA ingress test can definitively confirm a leak. Learn how to perform this critical quality test.

  4. An Advanced Single-Use Solution for Downstream Bioprocessing 9/5/2023

    A single-use chromatography system is offering an innovative solution tailored to meet the needs of evolving downstream purification bioprocesses.

  5. Thermo Fisher Scientific Large Volume Liquid Expansion 5/2/2024

    Take an insightful look into the expansion of the large volume liquids manufacturing site at the Grand Island facility, highlighting the various stages of the manufacturing process and the capabilities it offers to support the bioprocessing industry.

  6. Developing A 2-Step Chromatographic Process For The Purification Of AAV Vectors 6/24/2025

    POROS CaptureSelect AAVX and POROS 50 HQ were tested for capture and polishing, respectively, of AAV2, AAV9 and a novel engineered capsid to achieve vectors with high purity and significant empty: full ratio improvement.

  7. Upstream To Downstream: A Comprehensive Approach To AAV Production 12/7/2023

    How can you face the challenges of AAV production, scale up your AAV manufacturing effectively, and enhance the recovery and purity in your downstream processing.

  8. Affinity Resins Overview 6/16/2025

    We have developed a unique portfolio of affinity resins to help you develop biosimilars, biobetters, and other types of recombinant proteins. These affinity resins can be used for clinical and commercial production.

  9. CaptureSelect Affinity Chromatography 11/4/2025

    30-second video sharing a visualization of our CaptureSelect affinity chromatography capability. The target protein binds with VHH molecules immobilized on the chromatography beads, non-target proteins are removed, and the eluted fraction contains a high yield of purified target protein.

  10. Streamlining Vaccine Development, Production With Modality-Specific Purification Tools 6/5/2025

    Novel vaccine purification tools are speeding up development for mRNA, viral vectors, and VLPs. Learn how specific chromatography resins can enhance rapid screening and downstream processing.