Downstream Processing

  1. Enhancing AAV Purification In Gene Therapy Manufacturing 6/2/2025

    Review chromatography solutions for purifying multiple AAV serotypes, with specialists’ insights on bioprocessing and downstream optimization.

  2. BioTitan Retention Device Overview 5/29/2025

    Learn about a retention device that provides robust fortification for single-use assemblies. Its 360-degree seal strengthens connections, reduces leak risks, and ensures process integrity for fluid transfer.

  3. Quality Roundtable: Optimizing Biologics Manufacturing Processes With Raw Materials 1/24/2024

    Improve your commercial manufacturing process with advice from regulatory and raw materials experts on the development journey from pre-clinical to licensure.

  4. Streamlining Vaccine Development, Production With Modality-Specific Purification Tools 6/5/2025

    Novel vaccine purification tools are speeding up development for mRNA, viral vectors, and VLPs. Learn how specific chromatography resins can enhance rapid screening and downstream processing.

  5. Process Intensification Development Challenges At AZ and AbbVie 8/27/2024

    In this segment of the Bioprocess Online Live event Bioprocess Intensification In The Real World, panelists respond to audience questions about the challenges they’ve encountered while developing process intensification strategies.

  6. What Bioprocessing Bottlenecks Does Process Intensification Address? 8/27/2024

    Supply chains, consumables, and data are identified as three of the management challenges that intensified processes and process automation technology (PAT) are addressing at AbbVie and AstraZeneca.

  7. Beyond Standard Protein A Resin 6/2/2025

    In this study, mAbCapture C affinity resin has been compared with a Protein A resin used in a DSP platform, showing a higher dynamic binding capacity while keeping the product’s critical quality attributes within acceptable limits.

  8. Thermo Fisher Scientific Bio-Expo Live 2024: Downstream Bioprocessing 8/15/2024

    Review downstream process tools from Thermo Fisher Scientific to enable optimal biologics purification, including chromatography resins, chemicals, process liquids, and buffers.

  9. Enhancing Aseptic Fill-Finish Processes 7/3/2025

    Achieve exceptional product recovery and sterility. Learn about high-integrity surge bags, advanced leak detection, and flexible design options for your fill-finish applications.

  10. Developing A 2-Step Chromatographic Process For The Purification Of AAV Vectors 6/24/2025

    POROS CaptureSelect AAVX and POROS 50 HQ were tested for capture and polishing, respectively, of AAV2, AAV9 and a novel engineered capsid to achieve vectors with high purity and significant empty: full ratio improvement.