Insights On Upstream Manufacturing

  1. 9 Considerations When Buying Used Laboratory Equipment 2/24/2026

    Before purchasing used lab equipment, evaluate contamination risks, service history, and manufacturer support. Ensure short-term savings do not compromise your long-term research reliability.

  2. Krakatoa® K500: A Seismic Shift In Media And Buffer Consumption 2/24/2026

    Learn how point-of-use media manufacturing delivers 30-50% cost savings while eliminating cold chain logistics, improving consistency, and accelerating advanced therapy production timelines.

  3. Steady & Stable From Lab To Launch: Seamless Scale-Up With The First And Only GMP Transfection Stabilizer 2/24/2026

    Learn how extended transfection stability windows and reduced complex volumes solve critical scale-up challenges in AAV and lentivirus manufacturing at 1000+ liter production scales.

  4. Avoiding Common Real-World Pitfalls In Viral Clearance Studies 2/24/2026

    Viral clearance studies face regulatory uncertainty, process limits, timeline pressure, and design challenges, demanding phase‑appropriate, flexible strategies for reliable outcomes.

  5. mRNA Manufacturing With Fed-Batch In Vitro Transcription 2/13/2026

    A milliliter-scale approach to IVT optimization reveals how controlled feeding, precise pH management, and real-time monitoring can boost mRNA yield and streamline scale-up to larger bioreactor volumes.

  6. A Comprehensive Solution For Adventitious Agent Testing 2/13/2026

    Modern sequencing methods offer sensitive detection of adventitious and species‑specific viruses. Learn how targeted and non‑targeted NGS approaches improve confidence in cell bank characterization.

  7. A Faster, More Sensitive Approach To Virus Detection 2/13/2026

    Discover a faster, more sensitive approach to rodent virus detection that offers a targeted NGS workflow to help uncover contaminants traditional assays may miss.

  8. CHO K1 Cell Culture Process Intensification For Enhanced Production Of IgG mAbs 2/12/2026

    Discover how our optimized CHO K1 cell lines achieved up to an 80% increase in titer while maintaining product quality through molecule-specific process development strategies.

  9. The Science Of Cell Line Development For Biologics 2/12/2026

    Selecting and engineering the right cell line is not simply a technical milestone; it is a strategic decision that shapes cost of goods, development timelines, and the overall probability of success.

  10. Flexibility Or Scale? Navigating The Single Use Vs. Stainless Steel Debate 2/12/2026

    Explore how to choose between single‑use and stainless‑steel bioreactors, outlining key advantages, limitations, and long‑term considerations essential for successful biologics scale‑up.