Insights On Upstream Manufacturing

81. Maximizing MSC Yield And Quality: A Comparative Media Study 11/3/2025

    Maximize mesenchymal stem cell (MSC) expansion with a simplified culture process. New data demonstrates a high-performance, xeno-free media that eliminates the need for coatings or media exchanges.

82. Comparing Advanced Cell Culture Vessels vs. Traditional Options 10/31/2025

    Learn how innovative cell culture vessel design enables high-density cell growth with superior gas exchange and a closed system to scale up bioproduction efficiently while maintaining batch-to-batch consistency.

83. Cytokines For Ex Vivo Cell Culture 10/29/2025

    Comparable T cell expansion and function between cytokine sources were demonstrated. Generated CAR-T cells showed robust cytotoxicity and lower exhaustion markers.

84. Walk-Away Monitoring Of Cytotoxicity, Viability, And Apoptosis 10/29/2025

    Real-time cell health monitoring reveals how drug dose and timing impact apoptosis, necrosis, and viability. Explore how automated workflows help pinpoint mechanistic toxicity windows.

85. Getting The Most Out Of Cell-Based Assays With The Optimal Read Function 10/29/2025

    Gain insight into a whole-well fluorescence analysis that improves sensitivity and reproducibility in cell-based assays by accounting for uneven cell distribution.

86. The Case For Optimized And Excipient GMP Cell Culture Solutions 10/27/2025

    Learn how optimized, customizable formulations and Excipient GMP manufacturing streamline development, ensuring quality and consistency for a de-risked path to the clinic.

87. A Simple And Accurate Method To Quantify Molar Concentrations 10/24/2025

    Explore a fast, size-independent method for NGS library quantification that improves accuracy, reduces workflow time, and ensures consistent sequencing results without the need for qPCR.

88. Advance Long-Term Cell Kinetics With Integrated Fluid Handling 10/24/2025

    Examine how a novel setup enables uninterrupted long-term cell-based assays by combining CO₂ regulation and evaporation control to improve cell viability and data consistency for real-time analysis.

89. Smarter CMC Strategies To Accelerate Next-Gen Biologics To The Clinic 10/23/2025

    Learn how process design and cross-functional collaboration mitigate risks and accelerate the path from early development to FIH manufacturing through real-world case studies of practical approaches.

90. Cell Culture Media Filtration: Evaluating Cell Culture Performance 10/23/2025

    Cell culture performance remained consistent across PES and PVDF filters, even under worst-case filtration conditions. Discover a practical framework for evaluating membrane impact on CHO cell growth.