Formulation White Papers & Case Studies

1. Overcoming Excipient Risks And Challenges For Parenteral Formulations 8/27/2025

   Excipients are essential to parenteral formulations, which help protect APIs, enhance stability, and ensure safety. Learn how strategic excipient selection can optimize drug performance and patient outcomes.

2. Stabilization Of RNA-Loaded Lipid Nanoparticles By Lyophilization 8/15/2025

   Discover how lyophilization enhances RNA-based therapeutics by enabling storage at higher temperatures, which simplifies cold-chain logistics while preserving nanoparticle integrity and biological activity.

3. Tangential Flow Filtration Of LNPs Results In 10X Concentration Within 20 Minutes 8/5/2025

   Dive into a study that details how a single-pass tangential flow filtration system can achieve a tenfold concentration of liposomal nanoparticles in under 20 minutes.

4. Enhanced Structural Characterization Of Thermal Unfolding With MMS 7/21/2025

   Explore the power of Microfluidic Modulation Spectroscopy (MMS) in resolving distinct melting behaviors and domain-specific unfolding events for biologics, providing crucial structural insights for development and formulation.

5. Non Animal Origin Squalene For High-Risk Applications 7/21/2025

   Explore an ethical and sustainable alternative to shark-derived squalene that is backed by robust data to deliver identical performance in vaccine formulations without environmental compromise.

6. Structural Characterization Of GLP-1 Analogues And Formulations Using MMS 7/9/2025

   Discover how MMS quantifies peptide concentrations and identifies structural differences in GLP-1 and its commercial analogues across various buffer systems.

7. Designing Protocols For A 40% Emulsifiable Concentrate Of A Systemic Insecticide 6/13/2025

   Explore how formulation expertise can help overcome the complex challenges of developing stable, effective, and regulatory-compliant emulsifiable concentrate (EC) formulations for crop protection.

8. CQA Assessment Of LNP-Encapsulated IVT mRNA 4/21/2025

   Learn more about issued guidelines on Critical Quality Attributes for IVT mRNA vaccines and biotherapeutics to focus on drug substance and LNP-encapsulated drug product assessment using an analyzer system.

9. Replicate Bioscience And Cytiva Collaborate To Deliver srRNA-LNP Vaccines 3/24/2025

   Discover how self-replicating RNA (srRNA) can revolutionize vaccine development with sustained protein expression, lower doses, and fewer side effects to advance next-gen RNA therapeutics.

10. Formulation Through Manufacturing Under One Roof 2/18/2025

    Partner with a CDMO that understands the unique challenges of emerging biopharma, providing expert guidance in formulation development, manufacturing, and regulatory navigation.