Featured Articles
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Simplifying CHO Cell Line Genetic Stability Testing
4/11/2024
Here, we describe the use of whole genome sequencing to perform a comprehensive assessment of genetic stability in clonally derived CHO cell banks using the Aptegra™ CHO genetic stability assay.
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A Single, Comprehensive Method For Genetic Stability Testing
4/11/2024
Discover a genetic stability assay that is fully validated to GMP quality standards and outperforms traditional testing methods with its enhanced speed and accuracy.
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Leveraging Perfusion Early In Process Development For Better Commercial Outcomes
4/5/2024
By addressing the complex needs of cell culture from the start, organizations can take steps to optimize their process, ensuring they are maximizing productivity and product quality.
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Next Generation Conjugates: Process And Analytical Challenges
3/25/2024
Explore specific examples of challenges commonly encountered in the process and analytical development of next-generation conjugates as well as corresponding solutions for each.
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AAV Process Intensification Using High Salt Lysis And Salt Tolerant Endonuclease
3/25/2024
In the production of adeno-associated virus (AAV) vectors, cell lysis involves challenges addressed through high salt concentrations and a salt-tolerant endonuclease, enhancing titer and infectivity.
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AAV Process Intensification Using High Salt Lysis & Salt Tolerant Endonuclease
3/25/2024
Examine how intensifying AAV production with high salt lysis and Benzonase® Salt Tolerant endonuclease enhances viral yield and infectivity while ensuring DNA removal for patient safety.
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Formulation Process And Analytical Development Capabilities
3/21/2024
Explore process and analytical development capabilities that can help you advance your formulation to GMP Manufacturing.
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Advancing A LNP Formulation To Clinical And Commercial Manufacturing
3/21/2024
Lipid selection impacts the final LNP drug product and the LNP process. Review critical quality considerations for lipids and the process requirements for successful commercial-scale manufacturing.
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Contrast In Oligonucleotides
3/13/2024
Explore the differences between research-use-only oligonucleotides and those manufactured in compliance with GMP 21 CFR 820.
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Characterization Of Host Cell Proteins By Liquid Chromatography - Mass Spectrometry
2/26/2024
Explore an established liquid chromatography – tandem mass spectrometry (LC-MS/MS) method for characterization of residual HCPs in monoclonal antibody (mAb) products.