Featured Articles
-
mRNA Process And Cost Modeling: A Tool To Optimize Process Development
3/10/2023
Demand for mRNA-based medicine production continues to increase, as do investments in prophylactic and therapeutic indications. Explore a cost-model that compares all modalities.
-
Applying High Throughput Processes To Optimize AAV Titers
3/8/2023
A growing number of AAV product developers are recognizing the value in moving to suspension as early in development as possible in order to optimize production.
-
Viral Safety Handbook
3/6/2023
Since production templates depend on cell culture processes, biopharmaceuticals are susceptible to adventitious agent contamination. Explore a holistic overview of viral safety consolidating decades of expertise and process understanding.
-
Chromatography Solutions For AAV Full And Empty Capsid Separation
3/1/2023
Effective separation of full and empty AAV capsids requires implementation of purification strategies that differ from standard approaches used for traditional modalities. Explore two cases describing such approaches.
-
Performing A Tangential Flow Filtration (TFF) Optimization Study
2/14/2023
This application note describes the recommended methods and techniques for optimizing a tangential flow filtration (TFF) process using a Cogent® Lab system and the Bio4C® Control Software.
-
Implementing High Cell Density Cryopreservation In Your Seed Train
1/22/2023
Simplify seed train intensification with high cell density cryopreservation. Eliminate the need for manual scale-up steps and enable risk reduction through closed banking and inoculation processes.
-
Validation Master Plan For Filtration Systems Used In Aseptic Processing
1/13/2023
Regulatory guidance provides a framework for aseptic processing that ensures patient safety. Learn about the best practices for validating performance of critical filtration systems used in aseptic processing.
-
Capsules Versus Hollow Fibers For Ultrafiltration/Diafiltration (UF/DF)
1/13/2023
Explore the performance evaluation of a first-of-its-kind spiral-wound TFF filter versus hollow fibers for UF/DF of viral vectors and the impact of either filter type on a TFF process.
-
Biopharma 4.0: Convergence Of Information, Operations, And Processing Tech
1/7/2023
Biomanufacturers seeking a place in a competitive and lucrative future must start engaging in change now to meet the demands for delivering drugs more quickly to the patients who need them.
-
Using High Cell Density Cryopreservation For Seed Train Intensification
12/21/2022
The traditional seed train expansion process can be time consuming. Learn how seed train intensification techniques such as high cell density cryopreservation (HCDC) can accelerate and streamline the process.