Featured Articles

31. Improve Fed-Batch Yields With EX-CELL® Advanced, Cellvento® Cell Culture Media Portfolios 2/15/2022

    The biopharmaceutical industry is interested in developing high-titer fed-batch processes to meet increasing market demands and reduce manufacturing costs. This application note provides guidance and options for improving cell culture yield with off-the-shelf catalog products. Media combinations, dynamic fed-batch feeding options, and feed screening strategies suitable for diverse cell lines and manufacturing scenarios are presented.

32. White Paper: Process Analytical Technology (PAT) Using Next Generation Raman For Real-Time Bioprocess Monitoring 2/4/2022

    In this white paper, we describe applications and share case studies using Raman technology for real-time, inline monitoring of cell culture process parameters.

33. Multivariate Inter-Stage Batch Profile Monitoring And Future State Estimation For Efficient Manufacturing Operations 2/3/2022

    How much quicker and easier would it be if we could know the process’s health by looking at a single metric rather than checking hundreds of parameters?

34. Perspectives Of Value-Driven, Integrated Solutions In Gene Therapy 1/25/2022

    By unlocking the value of an integrated solutions provider, you can leverage a comprehensive suite of advanced technologies and expertise that will facilitate your path to market and benefit you for the lifetime of your product.

35. Multi-Column Capture Chromatography 1/5/2022

    Continuous capture chromatography allows for improved resin capacity, through continuous loading of multiple columns in series, reducing cost of goods.

36. Bulk Packaging For Cartridge Filters 12/17/2021

    Improve productivity, logistics and sustainability – sound easy? It is if you leverage new bulk packaging options that improve efficiency while reducing waste and footprint. Utilize the same high-quality product, delivered with less packaging and designed for productivity.

37. Cell Culture Media Prep: Filter Selection And Cell Culture Performance 12/17/2021

    Membrane filtration of cell culture media is a time-tested solution for reducing the risk of bioreactor contamination. This poster shows how membrane filter pore size and materials affect CHO cell culture media filtration and performance.

38. How To Intensify Your Blood Plasma IgG Purification 12/9/2021

    In this white paper, we present the results from our collaboration with Taipei Medical University to develop and evaluate the reliability and consistency of various new steps to purify plasma-derived IgG. 

39. Pandemic Playbook For Gene Therapy Manufacturing 10/21/2021

    A conversation that discusses the challenges to gene therapy development and manufacturing created by the pandemic and lessons learned from the rapid vaccine development efforts that can be applied to transform the gene therapy field going forward.

40. Development Of A Scalable Bioreactor Process For Transient Adeno-Associated Virus Serotype 2 (AAV2) Production 10/18/2021

    Review the development of a suspension based AAV upstream production process that provides a more efficient and cost-effective bioprocessing solution for large scale production.