Featured Articles
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AAV Process Intensification Using High Salt Lysis And Salt Tolerant Endonuclease
3/25/2024
In the production of adeno-associated virus (AAV) vectors, cell lysis involves challenges addressed through high salt concentrations and a salt-tolerant endonuclease, enhancing titer and infectivity.
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AAV Process Intensification Using High Salt Lysis & Salt Tolerant Endonuclease
3/25/2024
Examine how intensifying AAV production with high salt lysis and Benzonase® Salt Tolerant endonuclease enhances viral yield and infectivity while ensuring DNA removal for patient safety.
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Formulation Process And Analytical Development Capabilities
3/21/2024
Explore process and analytical development capabilities that can help you advance your formulation to GMP Manufacturing.
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Advancing A LNP Formulation To Clinical And Commercial Manufacturing
3/21/2024
Lipid selection impacts the final LNP drug product and the LNP process. Review critical quality considerations for lipids and the process requirements for successful commercial-scale manufacturing.
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Contrast In Oligonucleotides
3/13/2024
Explore the differences between research-use-only oligonucleotides and those manufactured in compliance with GMP 21 CFR 820.
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Characterization Of Host Cell Proteins By Liquid Chromatography - Mass Spectrometry
2/26/2024
Explore an established liquid chromatography – tandem mass spectrometry (LC-MS/MS) method for characterization of residual HCPs in monoclonal antibody (mAb) products.
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Strategies For The Separation And Analysis Of Empty And Filled Capsids
1/23/2024
Explore approaches for the capture and separation of capsids, upstream strategies for reducing the level of empty and partially filled capsids, trends in AAV capsid design impacting purification, and more.
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Scalability And Performance Of MobiusĀ® iFlex Bioreactors
1/19/2024
Utilizing single-use bioreactors in intensified fed-batch and perfusion processes can help manufacturers produce a high-quality drug supply while reducing facility footprint and production costs.
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Perspectives On The Adoption Of Fully Closed Processing
1/16/2024
In this study, industry experts share their perspectives and plans related to the implementation of fully closed processing. Explore the drivers and challenges of fully closed processing and more.
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Streamlining And Enhancing Gene Therapy Production With Automation
1/9/2024
When it comes to determining the appropriate analytics to inform early development, there are a number of variables to consider surrounding cost, operator expertise, and throughput.