Virus Retention Performance Of Viresolve® Pro Devices Under A Range Of Processing Conditions

A strong viral clearance strategy depends on more than just good filtration—it requires confidence that virus retention won’t falter under real-world process conditions. Recent data confirms that size-exclusion-based viral filters maintain high Log Reduction Values (LRVs) for small viruses, even when key variables like protein concentration, pH, conductivity, temperature, and pressure fluctuate. The findings show that virus retention is governed primarily by membrane pore size, not by shifts in the process environment. This consistency simplifies risk assessments and supports a streamlined validation approach. For teams navigating regulatory expectations like ICH Q9, these insights offer a compelling case for reducing complexity without compromising safety.

Explore how this data can help you build a more efficient, compliant viral clearance strategy.