Downstream Processing Featured Articles

  1. Revision Of The EU GMP Guide: EU Commission Publishes Proposals For Chapters 3, 5, 6 And 8 1/24/2013

    On 17 January 2013, the EU Commission published the drafts of 4 revised chapters of the EU GMP Guide. The publication had been expected for a long time now.

  2. Saint-Gobain's New C-Flex® ULTRA Pump Tubing For Biopharmaceutical Applications Outperforms The Competition 6/28/2012

    Saint-Gobain Performance Plastics has expanded its line of thermoplastic elastomer (TPE) tubing with the addition of new C-Flex® ULTRA pump tubing, a product designed specifically to perform in demanding biopharmaceutical applications such as pumping, single-use assemblies, process filling and sampling.

  3. Success Of Engineered Tissue Depends On Where It's Grown 8/14/2012

    Tissue implants made of cells grown on a sponge-like scaffold have been shown in clinical trials to help heal arteries scarred by atherosclerosis and other vascular diseases. However, it has been unclear why some implants work better than others. By Anne Trafton

  4. How Can You Mitigate The Risks Of Single-Use Bags? 8/24/2015

    The loss of product as a result of bag failure isn’t just an annoyance; it’s an expense, and a costly one at that. However, Chuck Hart, director of manufacturing at Prolong Pharmaceuticals, says with proper fitting and handling, these concerns can be mitigated.

  5. Untapped Potential Of Protein A To Be Highlighted At BPI Conference 8/19/2015

    Pete Gagnon, group manager for downstream processing at the Bioprocessing Technology Institute in Singapore, discusses his upcoming presentation at the 2015 BioProcess International (BPI) Conference. Protein A: the Fine Print, is one of several scheduled during the pre-conference symposia track, Innovation in Process and Product Development Technologies for Biopharmaceutical Development.

  6. International Stem Cell Corporation Demonstrates Positive Animal Efficacy Results In Metabolic Liver Disease Program 2/12/2013

    International Stem Cell Corporation (OTCQB: ISCO) (www.internationalstemcell.com) ("ISCO" or "the Company") a California-based biotechnology company, today announced the conclusions from its study demonstrating the efficacy and safety of the hepatocyte-like cells (HLC) derived from human parthenogenetic stem cells (hpSC) in a well-established animal model of a congenital liver disorder associated with bilirubin metabolism.

  7. Scientists Help Identify A Missing Link In Taste Perception 3/6/2013

    Working with a multidisciplinary consortium of 19 researchers from nine institutions, Monell scientists have provided critical information to identify CALHM1, a channel in the walls of taste receptor cells, as a necessary component in the process of sweet, bitter, and umami (savory) taste perception.

  8. BioPharma Industry Getting Comfortable With Complex Single-Use Devices 2/10/2012

    The rate of usage of disposables in biopharmaceutical manufacturing has increased substantially over the past six years in a variety of areas, but most notably for complex devices, that are also among the most expensive. By Eric Langer

  9. MicroRNAs Can Convert Normal Cells Into Cancer Promoters 11/21/2012

    Unraveling the mechanism that ovarian cancer cells use to change normal cells around them into cells that promote tumor growth has identified several new targets for treatment of this deadly disease.

  10. Vaccine And Antibiotics Stabilized So Refrigeration Is Not Needed 7/10/2012

    Researchers funded by the National Institutes of Health have developed a new silk-based stabilizer that, in the laboratory, kept some vaccines and antibiotics stable up to temperatures of 140 degrees Fahrenheit. This provides a new avenue toward eliminating the need to keep some vaccines and antibiotics refrigerated, which could save billions of dollars every year and increase accessibility to third world populations.