Downstream Manufacturing Solutions

  1. RoSS.FILL Bottle: Fill And Filter Your Drug Substance Into Single-Use Bottles 8/27/2025

    This automated system provides worry-free, high-accuracy filling and filtration of liquid drug substances into single-use bottles up to 10 liters, offering fast throughput and bottle independence.

  2. Jet-Based Nanoparticle Formulation At Research Scale 8/14/2025

    Developing nanoparticle formulations requires a scalable solution that replicates manufacturing conditions at a small scale. Turbulent jet mixing enables linear scalability while conserving materials.

  3. Accurate Single-Use Bag Filling System For Small Volumes 8/4/2025

    RoSS.FILL CGT is a flexible platform for dispensing operations into single use bags and bulk filtration that are supported by RoSS systems. The fluid path is designed to be fully disposable and is able to accommodate a variety of sterile connection and disconnection options.

  4. IRIS Single-Use Assemblies: Fluid Management Made Simple 8/4/2025

    Achieve fluid management goals of modular configuration, cutting-edge quality, and the shortest lead time with a single-use assembly & tubing system

  5. Purolite™ AP+ Resin Platform: Advanced Purification To Improve Manufacturing Efficiencies 8/4/2025

    This advanced resin platform optimizes performance, accelerates timelines, and reduces costs for enhanced manufacturing efficiency.

  6. A High-Capacity Chromatography Resin For Robust mAb Capture 7/31/2025

    Protein A chromatography resin with excellent capacity and alkaline stability for cost-efficient and extremely robust mAb capture.

  7. RoSS.PPST: Pre-Use Post Sterilization Integrity Testing 7/30/2025

    Ensure drug product sterility with automated pre-use post-sterilization integrity testing. Learn about a system that proactively detects filter failures, minimizing contamination risks.

  8. Used Turn-Key Modular Systems (TKMS) Tangential Flow Filtration Skid 7/28/2025

    Unused Turn-Key Modular Systems (TKMS) Tangential Flow Filtration (TFF) system. This TFF unit is designed to remove ethanol from the process stream (via diafiltration, where a buffer exchange occurs to a required number of diavolumes). The system consists of: - UF Filter: Repligen model KROSFLOW MAX X06-E100-05-N for solvent removal and buffer exchange, CIP and SIP rated, 12,000 fiber count, 128,000 square-centimeter surface area (12.8 square-meters). - Filter cartridge & housing: Allegheny Bradford Corp. Model OC-1-01-QT49394-2 Air and Clean Steam Filter, 316L SS construction, design pressure FV to 150 psig, design temperature -20 to 350F (SIP temp approx. 121C). - Feed Pump: Waukesha Cherry-Burrell model 220-U2 positive displacement pump (100 lpm min/ 600 lpm max) - GEMU, Steriflow , and PBM valves - Optek UV Analyzers (not Ex rated) - Instrumentation: Bronkhorst, Endress & Hauser, and others - Sample holder: Millipore model AT51/5-3E0 - Aflex Hose - 316L stainless steel product contact parts - Stainless steel skid frame - Built to comply with "ATEX Zone 2 II 3G Ex" standards - FAT performed still on original shipped skid from OEM.

  9. Prepare For Successful Biomarker Profiling From Cell-Free DNA 7/14/2025

    Discover how standardized preanalytical practices for cell-free DNA can enhance liquid biopsy accuracy, which enables reliable detection of genomic and epigenetic alterations for improved diagnostics.

  10. A Complete CRISPR Workflow From The Lab To The Clinic 7/3/2025

    Explore a complete, end-to-end genome editing solution designed to support seamless transitions from lab research to clinical applications with precision and efficiency.