Downstream Isolation and Purification

  1. Virus Clearance By Chromatography 7/13/2018

    This video features a presentation of the analysis of the over all performance of different chromatography types based on their internal database looking specifically for the log reduction factors for the most testable viruses; MuLV, MVM, PRV, and Reo-3.

  2. A Scalable Immobilized Metal Affinity Chromatography Media For Process Purification 5/6/2021

    Downstream process purification of proteins requires a resin with optimized bead size for ideal pressure/flow properties and decent dynamic binding capacity DBC that provides production efficiencies and good process economics. This video explains how our newly developed metal chelate affinity resin — Nuvia IMAC — provides the mechanical strength, pore structures, ligand density, and particle size distribution required for an operation run at 300 cm/hr with a DBC of 40 mg/ml at 2 bar column backpressure.

  3. How To Select Your DSP Chromatography Technology? 6/7/2021

    Making the switch from single batch to multi-column chromatography can dramatically reduce resin utilization, costs and eliminate bottlenecks without sacrificing quality. This animated feature compares the traditional, single batch approach to a multi-column alternative for mAb capture.

  4. Robust Workflow For Single Cell Cloning Of iPSCs For Making cGMP Master Cell Banks 3/7/2022

    We demonstrate a platform combination of Solentim instrumentation (the VIPS™) and soluble matrix (MatriClone™, based on laminin) for the high-efficiency, high-viability single-cell cloning of iPSCs to form the Master Cell Bank.

  5. Introducing The Series 4000™ Single Round Filter Housings 10/13/2020

    Reliable filter housing design to meet all your biopharmaceutical filtration needs. The Series 4000™ Filter Housings are available in T-line and in-line designs, with a wide range of tube sizes. All configurations are available and ready to be shipped to your location!

  6. Navigating The Diverse Antibody Pipeline With Chromatography Innovations 5/23/2022

    Choosing a suitable resin for your purification needs doesn’t have to be daunting. Learn more about how to select the right resin for your antibody variant purification project.

  7. Single-pass Tangential Flow Filtration For Bioprocessing 4/2/2020

    Experiencing bottlenecks in your downstream process? Pellicon® Single-Pass TFF increases your productivity, capacity while reducing costs!

  8. Mobius® Chrom 20 System, For Purification Of Clinical And Process Scale Biologics 10/13/2020

    Our unique clamshell and single-use Flexware® clamshell assemblies offers ultimate ease of use.

  9. Transform Your Chromatography Processes With An Innovative Approach 12/2/2024

    Learn how to achieve better resin utilization, minimize disruption to existing methods, and align your strategy with unique process goals.

  10. Redefine Your Oligonucleotide Manufacturing 4/22/2025

    Streamline oligo production and scale confidently. Explore high-performing, purpose-built automated equipment designed to ensure safety, efficiency, and purity, from synthesis through concentration.