Downstream Isolation and Purification

  1. How To Select Your DSP Chromatography Technology? 6/7/2021

    Making the switch from single batch to multi-column chromatography can dramatically reduce resin utilization, costs and eliminate bottlenecks without sacrificing quality. This animated feature compares the traditional, single batch approach to a multi-column alternative for mAb capture.

  2. Process-Scale Packing Guidelines: CHT™ Ceramic Hydroxyapatite 10/12/2017

    This video demonstrates proper packing technique, provides practical media handling tips, and gives specifications for optimal hardware and process conditions.

  3. Purification Platform For IgMs 9/21/2018

    Understand the challenges of IgM purification and how to design a scalable non-affinity based purification platform for manufacture of diagnostic IgMs.

  4. Development Of A cGMP-Ready Purification Process, Carsten Voß Video 4/12/2016

    Purification results are presented of a cGMP-ready process developed for a recombinant adenovirus. The two-step column process results in an adenovirus preparation with high yield and very low host cell protein (HCP) and DNA contamination, comparable to clinical grade products.

  5. Single-pass Tangential Flow Filtration For Bioprocessing 4/2/2020

    Experiencing bottlenecks in your downstream process? Pellicon® Single-Pass TFF increases your productivity, capacity while reducing costs!

  6. Chromatography Support Solutions 7/13/2018

    This video highlights Bio-Rad services including the development and optimization of purification platforms to meet today's manufacturing demands.

  7. Droplet Digital PCR Systems 9/21/2018

    Droplet Digital PCR (ddPCR) simplifies the quantification of host cell DNA in process development, quality control, and biomanufacturing processes.

  8. What Is The DynaChrom™ Single-Use Chromatography System? 3/21/2024

    This chromatography system offers a flexible solution, paired with an advanced software platform, allowing easy integration with downstream process automation.

  9. Optimized Purity Of A Monoclonal Antibody, Carsten Voß Video 4/12/2016

    Purity, recovery, and elution volume are important factors and parameters when screening multiple media (resins) for the development of efficient, robust, and economical production processes.

  10. Resolute® BioSMB Multi-Column Chromatography 12/2/2024

    Learn how to achieve better resin utilization, minimize disruption to existing methods, and align your strategy with unique process goals.