Downstream Isolation and Purification

  1. Chromatography Resins And Continuous Bioprocessing 7/13/2018

    In this video Bio-Rad's Process Chromatography Consultant, Jim Sulzberger speaks about continuous bioprocessing and chromatography resins.

  2. MilliporeSigma Large Scale Capabilities Tour 10/20/2021

    A detailed look at MilliporeSigma’s new BioReliance® viral vector manufacturing facility and how we have employed the latest innovations and quality systems to deliver best-in-class gene therapy services.

  3. A Scalable Immobilized Metal Affinity Chromatography Media For Process Purification 5/6/2021

    Downstream process purification of proteins requires a resin with optimized bead size for ideal pressure/flow properties and decent dynamic binding capacity DBC that provides production efficiencies and good process economics. This video explains how our newly developed metal chelate affinity resin — Nuvia IMAC — provides the mechanical strength, pore structures, ligand density, and particle size distribution required for an operation run at 300 cm/hr with a DBC of 40 mg/ml at 2 bar column backpressure.

  4. Explore Selectivity With Eshmuno® CMX Chromatography Resin 6/19/2020

    Eshmuno® CMX chromatography resin is a highly selective mixed mode chromatography resin for difficult to purify mAbs, ADCs and fusion proteins.

  5. Perform Multiple Chromatography Steps On A Single System 2/26/2024

    The Resolute® BioSC platform is a highly modular multi-step chromatography system designed to purify biologics. The platform can be configured to design your own multi-step process.

  6. Navigating The Diverse Antibody Pipeline With Chromatography Innovations 5/23/2022

    Choosing a suitable resin for your purification needs doesn’t have to be daunting. Learn more about how to select the right resin for your antibody variant purification project.

  7. What Makes A High-Quality Chromatography Resin? 9/26/2022

    The demand for resins for the manufacture of biological medicines is increasing every year. Walk through the process of what makes a high-quality chromatography resin.

  8. How To Select Your DSP Chromatography Technology 10/16/2024

    Watch to explore the differences between the conventional single-column batch method and the multi-column approach for mAb capture.

  9. Meet The Experts: Part 1 - Process Analytical Technology (PAT) 5/1/2023

    Watch part 1 of this 4-part interview series to learn about process analytical technology (PAT) from expert Stacy Shollenberger.

  10. Robust Workflow For Single Cell Cloning Of iPSCs For Making cGMP Master Cell Banks 3/7/2022

    We demonstrate a platform combination of Solentim instrumentation (the VIPS™) and soluble matrix (MatriClone™, based on laminin) for the high-efficiency, high-viability single-cell cloning of iPSCs to form the Master Cell Bank.