Downstream Isolation and Purification

  1. Your Roadmap For Efficient Processes 3/4/2025

    Struggling with mRNA integrity? Discover essential strategies to boost stability in mRNA manufacturing with innovative endonuclease-free DTT and Spermidine chemicals.

  2. Robust Workflow For Single Cell Cloning Of iPSCs For Making cGMP Master Cell Banks 3/7/2022

    We demonstrate a platform combination of Solentim instrumentation (the VIPS™) and soluble matrix (MatriClone™, based on laminin) for the high-efficiency, high-viability single-cell cloning of iPSCs to form the Master Cell Bank.

  3. Explore Selectivity With Eshmuno® CMX Chromatography Resin 6/19/2020

    Eshmuno® CMX chromatography resin is a highly selective mixed mode chromatography resin for difficult to purify mAbs, ADCs and fusion proteins.

  4. Purification Strategies For Multispecifics 6/2/2025

    In this segment from the Bioprocess Online Live event, “Challenges And Considerations For Purifying Multispecific Molecules,” our panelists Mark Fitchmun and Dr. Jian Ren debate the use of affinity resins compared to ion exchange and multimodal chromatography methods.

  5. Transform Your Chromatography Processes With An Innovative Approach 12/2/2024

    Learn how to achieve better resin utilization, minimize disruption to existing methods, and align your strategy with unique process goals.

  6. Simplify Your Process Of Choosing An Optimal Resin 5/19/2025

    Discover how to address evolving biotherapeutic purification challenges with a diverse resin portfolio and an intuitive Resin Selection Tool designed to streamline workflows and enhance production efficiency.

  7. Strategies For Viral Inactivation And Filtration In Multispecifics 6/2/2025

    In this segment from the Bioprocess Online Live event, “Challenges And Considerations For Purifying Multispecific Molecules,” our panelists cover molecule sensitivity to low pH and the use of detergent-based viral inactivation, as well as evaluating the suitability of platform viral filters.

  8. How To Select Your DSP Chromatography Technology? 6/7/2021

    Making the switch from single batch to multi-column chromatography can dramatically reduce resin utilization, costs and eliminate bottlenecks without sacrificing quality. This animated feature compares the traditional, single batch approach to a multi-column alternative for mAb capture.

  9. Redefine Your Oligonucleotide Manufacturing 4/22/2025

    Streamline oligo production and scale confidently. Explore high-performing, purpose-built automated equipment designed to ensure safety, efficiency, and purity, from synthesis through concentration.

  10. Chromatography Support Solutions 7/13/2018

    This video highlights Bio-Rad services including the development and optimization of purification platforms to meet today's manufacturing demands.