Downstream Isolation and Purification

  1. A Scalable Immobilized Metal Affinity Chromatography Media For Process Purification 5/6/2021

    Downstream process purification of proteins requires a resin with optimized bead size for ideal pressure/flow properties and decent dynamic binding capacity DBC that provides production efficiencies and good process economics. This video explains how our newly developed metal chelate affinity resin — Nuvia IMAC — provides the mechanical strength, pore structures, ligand density, and particle size distribution required for an operation run at 300 cm/hr with a DBC of 40 mg/ml at 2 bar column backpressure.

  2. Mobius® Chrom 20 System, For Purification Of Clinical And Process Scale Biologics 10/13/2020

    Our unique clamshell and single-use Flexware® clamshell assemblies offers ultimate ease of use.

  3. Chromatography Resins And Continuous Bioprocessing 7/13/2018

    In this video Bio-Rad's Process Chromatography Consultant, Jim Sulzberger speaks about continuous bioprocessing and chromatography resins.

  4. Concentrate Your Product After One Path With Pellicon® Single Pass Tangential Flow Filtration 4/2/2020

    Discover Pellicon® Single-Pass Tangential Flow Filtration, the versatile ultrafiltration technology for process intensification.

  5. Transform Your Chromatography Processes With An Innovative Approach 12/2/2024

    Learn how to achieve better resin utilization, minimize disruption to existing methods, and align your strategy with unique process goals.

  6. Explore Selectivity With Eshmuno® CMX Chromatography Resin 6/19/2020

    Eshmuno® CMX chromatography resin is a highly selective mixed mode chromatography resin for difficult to purify mAbs, ADCs and fusion proteins.