Downstream Isolation and Purification

1. How To Select Your DSP Chromatography Technology 10/16/2024

   Watch to explore the differences between the conventional single-column batch method and the multi-column approach for mAb capture.

2. Single-pass Tangential Flow Filtration For Bioprocessing 4/2/2020

   Experiencing bottlenecks in your downstream process? Pellicon^® Single-Pass TFF increases your productivity, capacity while reducing costs!

3. Meet The Experts: Part 1 - Process Analytical Technology (PAT) 5/1/2023

   Watch part 1 of this 4-part interview series to learn about process analytical technology (PAT) from expert Stacy Shollenberger.

4. Robust Workflow For Single Cell Cloning Of iPSCs For Making cGMP Master Cell Banks 3/7/2022

   We demonstrate a platform combination of Solentim instrumentation (the VIPS™) and soluble matrix (MatriClone™, based on laminin) for the high-efficiency, high-viability single-cell cloning of iPSCs to form the Master Cell Bank.

5. Transform Your Chromatography Processes With An Innovative Approach 12/2/2024

   Learn how to achieve better resin utilization, minimize disruption to existing methods, and align your strategy with unique process goals.

6. Perform Multiple Chromatography Steps On A Single System 2/26/2024

   The Resolute^® BioSC platform is a highly modular multi-step chromatography system designed to purify biologics. The platform can be configured to design your own multi-step process.

7. A Scalable Immobilized Metal Affinity Chromatography Media For Process Purification 5/6/2021

   Downstream process purification of proteins requires a resin with optimized bead size for ideal pressure/flow properties and decent dynamic binding capacity DBC that provides production efficiencies and good process economics. This video explains how our newly developed metal chelate affinity resin — Nuvia IMAC — provides the mechanical strength, pore structures, ligand density, and particle size distribution required for an operation run at 300 cm/hr with a DBC of 40 mg/ml at 2 bar column backpressure.

8. MilliporeSigma Large Scale Capabilities Tour 10/20/2021

   A detailed look at MilliporeSigma’s new BioReliance® viral vector manufacturing facility and how we have employed the latest innovations and quality systems to deliver best-in-class gene therapy services.

9. Introducing The Series 4000™ Single Round Filter Housings 10/13/2020

   Reliable filter housing design to meet all your biopharmaceutical filtration needs. The Series 4000™ Filter Housings are available in T-line and in-line designs, with a wide range of tube sizes. All configurations are available and ready to be shipped to your location!

10. Navigating The Diverse Antibody Pipeline With Chromatography Innovations 5/23/2022

    Choosing a suitable resin for your purification needs doesn’t have to be daunting. Learn more about how to select the right resin for your antibody variant purification project.