Bioprocessing White Papers
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Purity Analysis Methods For Synthetic Prime Editing Guide RNAs
9/8/2023
Develop a fast, easy workflow for the purity analysis of complex pegRNA molecules along with a robust denaturing technique for pegRNA with high levels of secondary structure.
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Add A 3rd Dimension To Your Immunoassay
9/7/2023
If you are seeking protein size separation information in addition to immunodetection of protein target(s) of interest, these assay can more provide sensitive, accurate, and reproducible read-outs than ELISA.
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Guide To Seeding, Expanding, And Harvesting Stem Cells
9/5/2023
Investigate important considerations for working with three different stem cell types: mesenchymal stem/stromal cells, induced pluripotent stem cells, and neural stem cells.
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Single-Use vs. Stainless Steel Debate In Biopharmaceutical Manufacturing
9/1/2023
Investigate the advantages and disadvantages of single-use technologies and stainless steel systems with a focus on performance, adaptability, and economics.
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Comparing Single-Use To Fixed Bioprocessing Systems
9/1/2023
Several life cycle assessments have been conducted comparing the environmental impact of SUTs to conventional fixed systems, leading to results that could inform changes in bioprocess system use.
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Sterile Filtration And Quality Risk Management
8/31/2023
Process control is essential for manufacturing sterile products. Explore the role of filtration for bioburden control in quality risk management and contamination control strategies.
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Eliminating USP <88> In Vivo Animal Bioreactivity Testing For Polymer Characterization
8/25/2023
There has been growing awareness about the environmental and ethical implications of plastics used in bioprocessing. The time for a shift to well-studied, proven in vitro cytotoxicity testing is now.
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AI Improving Inventory Management For Single-Use Systems Manufacturing
8/23/2023
The use of AI and machine learning tools can begin the process of moving from predictive, human-driven inventory management and manufacturing processes to genuine, data-driven decision making
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Recommendations For Successful IND Approval Of RNA-LNP Drugs
8/22/2023
The existing regulatory system is ambiguous for RNA therapeutics. Leverage this Investigational New Drug (IND) guide to help accelerate and strengthen the process IND filing of novel nanomedicines.
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Harnessing Amino Acid Derivatives To Improve Monoclonal Antibodies
8/20/2023
Recent research in the fast-growing market of monoclonal antibodies (mAbs) identifies excipients that reduce viscosity of high-concentration formulation and improve stability across a wide concentration range.