Bioprocessing White Papers

  1. Optimizing Poloxamer 188 1/13/2025

    Poloxamer 188 stabilizes proteins in liquid formulations and protects cells from shear stress. Molecular weight and hydrophobicity variations influence its effectiveness in different biopharmaceutical applications.

  2. Upscaling hMSC Production Enhances Extracellular Vesicle Secretion And Cargo Profile 12/19/2024

    Explore how the dynamic microenvironment of bioreactors influences the production and composition of extracellular vesicles (EVs), including exosomes, secreted by human mesenchymal stromal cells (hMSCs).

  3. Suspension Culture Improves iPSC Expansion And Pluripotency Phenotype 12/19/2024

    Learn about the advantages of 3D suspension culture for iPSC expansion, including enhanced pluripotency and genetic stability. Discover how this technique yields high-quality iPSCs for regenerative cell therapies.

  4. Effect Of NK-EVs And Carboplatin On Osimertinib-Resistant Lung Cancer Cells 12/18/2024

    Delve into a study that examines the possibility of the combination of NK-cell-derived EVs and CBP as a viable immunochemotherapeutic strategy for resistant cancers.

  5. State Of Validation Report 2024 12/17/2024

    Explore trends in compliance, audit readiness, digital systems, process efficiencies, emerging KPIs, and the adoption of Pharma 4.0 technologies.

  6. Driving Operational Excellence Using Machine Learning 12/13/2024

    Explore how advanced machine learning and data analytics are revolutionizing biopharmaceutical manufacturing and driving operational excellence.

  7. Accelerated Development Of Solid Oral Dosage Formulation For IND Submission 12/11/2024

    This paper highlights how the roller compaction process not only enhances efficiency but also improves the scalability of solid oral dosage production, supporting rapid development for regulatory approval.

  8. If You Can't Win The Game, Change It 12/11/2024

    Explore how eData sharing is used in the biopharma market, enabling standardized, collaborative supply chains that reduce risks and enhance visibility while improving capacity planning.

  9. Advancing Drug Safety And Improving R&D Productivity With The Liver-Chip S1 12/10/2024

    Explore how the Emulate Liver-Chip S1 revolutionizes predictive toxicology by mimicking human liver biology, achieving superior sensitivity and specificity.

  10. Tech Transfer At Risk: The Imperative For Digital Maturity, Modernization 12/2/2024

    Tech transfer is critical for biopharmaceutical production, but outdated tools can hinder the process. Discover how digital maturity can streamline operations, reduce risks, and accelerate time to market.