Biomanufacturing Featured Articles

1. A Novel In Vitro Glycosylation Approach For Difficult PTMs 2/19/2026

   Post-translational modifications of membrane proteins have been historically challenging. Research shows how an in vitro approach brings stability and predictability.

2. Active Versus Passive Shipping Solutions For Clinical Shipments 2/13/2026

   Explore active and passive temperature-controlled shipping solutions and their impact on clinical trial supply, balancing cost, risk, and product integrity.

3. Lyophilization: Protecting And Preserving Biologics 2/4/2026

   Discover how lyophilization revolutionizes biologic drug manufacturing and ensures potent, stable treatments for complex diseases.

4. The Hidden Challenges Of ADC Manufacturing - And How To Overcome Them 1/30/2026

   ADC manufacturing requires specialized expertise, single‑use systems, precise filtration, aseptic filling, and integrated lyophilization to ensure stability, safety, and consistent clinical‑grade production.

5. Evolving Methods Of Bulk Freezing 1/29/2026

   Learn how the transition to plate-based freezing with single-use technologies improves scalability and contamination control while ensuring uniform thermal transfer for high-value bulk drug substances.

6. How Reshoring, GLP-1s, And Supply Chain Security Are Transforming CDMOs 1/23/2026

   Explore how reshoring, GLP-1 capacity demands, and integrated U.S.-based manufacturing models are reshaping CDMO partnerships in a rapidly evolving pharmaceutical market.

7. Managing Supply Chain Risk In Scale-Up And Multisite Trials 1/23/2026

   Scaling trials across sites can lock in supply risk early. Learn how biologic variability, long lead times, and multisite complexity threaten trials and how to spot warning signs fast.

8. Integrated In Silico, Lab Assessments For Faster Drug Development 1/21/2026

   Integrated in‑silico and lab developability assessments flag molecular risks early, improving formulatability, manufacturability, and stability while reducing late‑stage failures, costs, and timelines.

9. Tailored, Cutting-Edge Lyophilization For Biologic Stability 1/21/2026

   Advanced lyophilization uses quality‑by‑design, predictive modeling, and tailored processes to boost biologic stability, reduce cold‑chain needs, and enable scalability for complex therapies.

10. Formulation: The Key To Long‑Term Success 1/21/2026

    Robust formulations protect long‑term biologic stability, safety, and efficacy by combining scientific insight, early modeling, and process‑aware development to handle variability.