Biomanufacturing Featured Articles

  1. The Hitchhiker´s Guide To Creating Oligonucleotides From Start To Finish 12/15/2025

    Producing high-quality oligonucleotides demands precise execution across multiple stages. Gain a clearer understanding of the complete mid-scale production workflow and necessary quality control measures.

  2. Four Reasons You Should Choose Lyophilization for Your Next Project 12/10/2025

    Lyophilization ensures product stability, extends shelf life, supports sensitive formulations, and simplifies storage and transport, making it a critical choice for modern drug development projects.

  3. Strained Manufacturing, Complexity Stymie In Vivo Progress 12/4/2025

     Explicitly mapping delivery challenges to the associated GMP process steps converts biological risk into operational risk.

  4. To Fight Cancer, Gene Editing Needs To Solve Its Delivery Problem 12/4/2025

    The choice of delivery dictates the complexity of manufacturing, which in turn determines the eventual cost and accessibility of the therapy.

  5. Controlled Nucleation Offers Homogeneity And Batch Consistency 11/24/2025

    Controlled nucleation standardizes freezing across all vials, leading to uniform ice crystals and improved lyo cake quality. This critical step reduces variability and supports robust product scale-up.

  6. Precision In Nanoparticle Processing And Monodispersed Lipid Nanoparticles For Advanced Therapeutics 11/17/2025

    Precision in nanoparticle processing is key for drug delivery and vaccines. Learn how monodispersed formulations enhance reproducibility and stability for next-generation therapeutics, like RNA-LNPs.

  7. Advancing RNA-LNP Therapeutics As An Alternative To Viral Vectors 11/17/2025

    RNA-LNP therapeutics offer a flexible, transient alternative to traditional viral vectors for genetic medicine. Learn about the advantages of LNPs in safety, scalability, and payload versatility.

  8. Supporting The Next Generation Of ADCs 10/30/2025

    Experts discuss innovation in antibody-drug conjugate (ADC) technology and how these impact CMC strategy. This summary captures key takeaways from the Bioprocess Online Live event "Evolving CMC Strategies To Enable Next-Gen ADCs."

  9. Freezing Bottles – 5 Critical Considerations 10/27/2025

    Learn five critical considerations for freezing bottles, including uniform rate control, container integrity, and selecting the right freezing technology to maintain product stability and process efficiency.

  10. New Guide Aims To Build Robust Framework For Digital Validation Tools 10/22/2025

    The ISPE's new guide addresses software for managing digital assets related to qualification, verification, validation, and compliance assurance.