Bioprocessing Application Notes & Case Studies

  1. Rapid Walkaway Solution For Assessing Viability In Cancer Organoids 3/31/2025

    Assess anti-cancer compounds' effects on organoid size and morphology with colorectal cancer organoids as well as discover automated imaging and viability assays to streamline drug screening and aid early identification.

  2. Parallel Line Analysis And Relative Potency 3/31/2025

    Explore parallelism testing methods, including response and parameter comparison tests, with innovative software to ensure accurate results with detailed protocols for linear and non-linear regression curves.

  3. Matrigel Dome Assay And Drug Screening Of Colorectal Cancer Organoids 3/31/2025

    Using CRC organoids and bioprinting, explore the automation of dome assays to evaluate drug responses and delve into the insights from image-based end-point assays on the efficacy of anti-cancer treatments.

  4. Fully Automated Cell Culture Passaging And Expansion 3/31/2025

    Automating cell culture tasks can reduce human error and free scientists from labor-intensive routines. Discover how imaging and automated systems enhance accuracy and reproducibility in cell culture processes.

  5. Unravelling Immunological Depths: Exploring Oxazolone-Induced Delayed-Type Hypersensitivity Model 3/28/2025

    Validating the oxazolone-induced DTH mouse model offers a critical platform for advancing the evaluation of therapeutic candidates for chronic inflammatory diseases, including atopic dermatitis.

  6. A Pre-Clinical Study For Diet-Induced Obesity 3/28/2025

    Here, we look at the importance of using high-fat diet-induced obesity models to evaluate and compare the efficacy of anti-obesity and anti-diabetic treatments like rimonabant and liraglutide.

  7. Optimizing Upstream Process Development To Increase mAb Titers 3/28/2025

    Uncover how we were able to help a client develop an efficient upstream process for a novel monoclonal antibody (mAb), resulting in a more than 100% increase in titers.

  8. Tag-Free Expression, in vivo Maturation, And Protein Purification 3/28/2025

    Optimizing recombinant expression and scalable purification strategies can help accelerate the production of challenging proteins, enabling successful program initiation and advancing pipelines.

  9. Introducing SUPR 3/28/2025

    Validating the performance of Getinge 50L and 250L single-use bioreactors alongside smaller-scale systems can optimize production processes and ensure scalability for CHO cell cultivation.

  10. A Translational Mouse Model For Non-Genetic Heterotopic Ossification 3/28/2025

    Reproducing the thermal lesion/tenotomy-induced mouse model can help overcome the challenge of unpredictable heterotopic ossification localization and enable the development of targeted interventions.