Case Study

Applications Of Membrane Adsorber Chromatography And Oligo-mAb Conjugation

Source: Abzena
GettyImages-1434627610 lab, manufacturing

Your oligonucleotide-monoclonal antibody (oligo-mAb) program deserves the best conjugation support, and that's what we deliver using our superior membrane adsorber technology.

In a recent case study with Sartorius, we demonstrated how our expertise in chromatography helped expedite the conjugation of an oligo-mAb program. Our chromatography processes are designed to efficiently remove impurities that arise during antibody-drug conjugate (ADC) and antibody-oligonucleotide conjugate (AOC) production. This includes free linkers and linker-payloads, aggregates, unwanted drug-to-antibody ratio (DAR) species, and more.

At Abzena, we've developed robust processes that use membrane adsorber technology, a more effective alternative to traditional resin-based chromatography.

Discover how our conjugation capabilities can accelerate your discovery program.

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