Bioprocessing Application Notes & Case Studies

  1. An Efficient End-To-End AAV8 Platform Process 11/5/2025

    Explore a scalable AAV production platform that improves full capsid yield and dramatically reduces host cell impurities, offering a practical solution to common manufacturing challenges.

  2. Use Cation Exchange Chromatography For High Yields In Vaccine Production 11/4/2025

    Learn how to achieve high yields in vaccine production by using Cation Exchange Chromatography for purifying SARS-CoV-2 spike proteins. This method provides high purity and minimizes protein aggregates.

  3. Expansion Of Human Bone Marrow-Derived MSCs 11/3/2025

    Achieving over 870 million viable, quality mesenchymal stem/stromal cells is possible. This efficient cell culture method scales bone marrow-derived MSCs for clinical needs.

  4. Maximizing MSC Yield And Quality: A Comparative Media Study 11/3/2025

    Maximize mesenchymal stem cell (MSC) expansion with a simplified culture process. New data demonstrates a high-performance, xeno-free media that eliminates the need for coatings or media exchanges.

  5. Enhancing CRISPR Knock-In And Knock-Out 10/29/2025

    Achieve scalable, non-viral CRISPR delivery for T cells. The next-generation electroporation platform provides robust, efficient gene editing in large-scale volumes.

  6. Cytokines For Ex Vivo Cell Culture 10/29/2025

    Comparable T cell expansion and function between cytokine sources were demonstrated. Generated CAR-T cells showed robust cytotoxicity and lower exhaustion markers.

  7. In Vitro Drug Screening On Cancer Cells 10/29/2025

    Explore a high-throughput assay combining stain-free imaging and multiplexed viability/toxicity measurements to evaluate drug effects on cancer cells, ideal for labs optimizing cell-based screening.

  8. Walk-Away Monitoring Of Cytotoxicity, Viability, And Apoptosis 10/29/2025

    Real-time cell health monitoring reveals how drug dose and timing impact apoptosis, necrosis, and viability. Explore how automated workflows help pinpoint mechanistic toxicity windows.

  9. Getting The Most Out Of Cell-Based Assays With The Optimal Read Function 10/29/2025

    Gain insight into a whole-well fluorescence analysis that improves sensitivity and reproducibility in cell-based assays by accounting for uneven cell distribution.

  10. Partner Case Study: Accelerating Gene Editing Manufacturing 10/28/2025

    Beam Therapeutics partnered with ElevateBio to manufacture BEAM-101, a novel base editing therapy for sickle cell disease, advancing rapid, high-quality production towards clinical trials.