Bioprocessing Application Notes & Case Studies

  1. Matrigel Dome Assay And Drug Screening Of Colorectal Cancer Organoids 3/31/2025

    Using CRC organoids and bioprinting, explore the automation of dome assays to evaluate drug responses and delve into the insights from image-based end-point assays on the efficacy of anti-cancer treatments.

  2. Fully Automated Cell Culture Passaging And Expansion 3/31/2025

    Automating cell culture tasks can reduce human error and free scientists from labor-intensive routines. Discover how imaging and automated systems enhance accuracy and reproducibility in cell culture processes.

  3. Unravelling Immunological Depths: Exploring Oxazolone-Induced Delayed-Type Hypersensitivity Model 3/28/2025

    Validating the oxazolone-induced DTH mouse model offers a critical platform for advancing the evaluation of therapeutic candidates for chronic inflammatory diseases, including atopic dermatitis.

  4. A Pre-Clinical Study For Diet-Induced Obesity 3/28/2025

    Here, we look at the importance of using high-fat diet-induced obesity models to evaluate and compare the efficacy of anti-obesity and anti-diabetic treatments like rimonabant and liraglutide.

  5. Optimizing Upstream Process Development To Increase mAb Titers 3/28/2025

    Uncover how we were able to help a client develop an efficient upstream process for a novel monoclonal antibody (mAb), resulting in a more than 100% increase in titers.

  6. Tag-Free Expression, in vivo Maturation, And Protein Purification 3/28/2025

    Optimizing recombinant expression and scalable purification strategies can help accelerate the production of challenging proteins, enabling successful program initiation and advancing pipelines.

  7. Introducing SUPR 3/28/2025

    Validating the performance of Getinge 50L and 250L single-use bioreactors alongside smaller-scale systems can optimize production processes and ensure scalability for CHO cell cultivation.

  8. A Translational Mouse Model For Non-Genetic Heterotopic Ossification 3/28/2025

    Reproducing the thermal lesion/tenotomy-induced mouse model can help overcome the challenge of unpredictable heterotopic ossification localization and enable the development of targeted interventions.

  9. A Comparative Efficiency Analysis Of Commercial Transfection Reagents In HEK 293 Cells 3/27/2025

    This study presents a detailed comparative analysis of the efficiency, viability, and cytotoxic effects of four widely used transfection reagents on Human Embryonic Kidney 293 (HEK293) cells.

  10. Bleomycin-Induced Scleroderma Mouse Model For Preclinical Testing 3/27/2025

    Get an in-depth overview of the bleomycin-induced scleroderma model, detailing its key specifications and presenting significant findings observed following bleomycin administration in study animals.