01.29.24 -- Why Lactococcus Lactis Might Be The Best Membrane Protein Factory

Explore opportunities with the introduction of high-capacity protein A resins, how and when multicolumn chromatography is beneficial, and how emerging technologies can address bottlenecks.

To execute complex viral product manufacturing, a service provider needs expertise in adherent cell culture capabilities, cell line productivity, and the intricacies associated with these products.

Developability profiles of biologics candidates help you avoid risk by collecting many quality attributes. Learn which attributes are evaluated during development and approaches for their measurement.

Learn how a fully disposable upstream and downstream platform process in antibody production can increase production timelines, enhance scalability, and reduce risk in biologics manufacturing.

This study demonstrates a microflow imaging system's ability to evaluate AAV9 particle purity and stability when subjected to heat stress at two different temperatures: 37 °C and 75 °C.

Capacity constraints typically are accompanied by other challenges, including missed timelines, defect rates, and overall decreased satisfaction with pharma companies’ bioprocessing CDMOs.

Investigate what drives the hypofunctional state of T cells in ICB-nonresponsive cancers through the characterization of CD8+ T-cell functionality in different tumor types. 

A critical issue when transitioning from stainless steel to plastic equipment is the presence of extractables and leachables (E&L). BPOG testing on single-use connectors mitigates the risks.

Minimize the risks of accelerated drug development processes and the potential use of new vaccine platform technologies with the use of a unique, laminated elastomer plunger.

Explore how a stepwise approach for process characterization can help target the right experimental design and be tailored for different programs based on prior knowledge and experience.

Explore important initial steps to consider and implement during the process design phase, which is a prerequisite to a successful PPQ campaign and readiness for commercial manufacturing.