05.30.24 -- How Advanced PAT Aids Quality By Digital Design In mRNA Manufacturing

This technology transfer study, conducted with cloud-connected bioreactors designed to accommodate CHO cells, compares results obtained from various shake flask cultures.

This powerful and easy to use batch planning strategy combines bioprocessing software and parallel bioreactors, enabling you to potentiate process development.

Build a reliable, de-risked path to the clinic while avoiding unforeseen costs and compliance-related delays with advice from Suparna Sanyal, Ph.D., Head of Viral Vectors Commercial Development.

By increasing recombinant AAV titers, this AAV enhancer can help reduce upstream manufacturing costs and lower the cost per therapeutic dose.

In this presentation, experts provide insight into genetic quality control, transposase-mediated genome engineering, and the maintenance of genetic stability in cell line generation.

This technology transfer study, conducted with cloud-connected bioreactors designed to accommodate CHO cells, compares results obtained from various shake flask cultures.

Here, we detail the upstream process development and optimization for an AAV8-GFP proof-of-concept (PoC) producer single cell clone (SCC) in both batch and perfusion modes.

Review the results of studies into the optimal method for cleaning and sterilizing a multi-use bioreactor, headplate, tubing, vent filters, liquid media and filled liquid addition bottle.

Gain insight into seed train intensification in upstream development, cell banking, and the challenges of cryopreservation processes from Khalil Essani, the Product Line Manager at Single Use Support.