03.08.24 -- Driving Pharma/Biotech Capacity With Smart Manufacturing

The biopharmaceutical industry is trending toward building process characterization systems and processes early in a project’s life cycle, enabling success for later-stage development.

Explore the vital role that laminar airflow technology plays in meeting sterile integrity standards and minimizing contamination risks in pharmaceutical cleanrooms.

ADC programs can accelerate through clinical phases rapidly, making early preparation for commercial launch imperative. It's sensible to partner with a CMO with a strong biologics foundation.

As innovative cancer therapeutics continue to enter the clinical trial pipeline, some developers are shifting their focus toward developing drugs that are safe and efficacious with minimal toxicity.

Protein A resins, with low flow rates and mass transport, lead to low productivity. Discover a solution that removes the bottleneck, offering a disposable alternative for mAb capture.

Glycosylation, a prevalent modification of mAbs, significantly impacts their function. Delve into various techniques for analyzing released glycans and their relative efficacy in HILIC-FLR-MS.

Examine a step-by-step approach outlining the business cases that support adopting continuous manufacturing, with considerations for innovators, generics manufacturers, CDMOs, and OTC suppliers.

Market dynamics will continue to favor engaging with CDMO partners who have the capabilities and experience to manage short-term needs while anticipating and planning for long-term requirements.

Uncover guiding principles to ensure that your CGT supply chain is future-proof and learn how an agile, flexible approach can help advance your project with reduced costs and delays.

Enable a wide array of genomic manipulation with the more regulated and efficient genomic insertion that's made possible by transposase-based technologies.

The time has come to move away from using non-human primates as test subjects in biomedical research and embrace more practical, reproducible, and cost-effective models.

Learn how the visualization of critical cellular responses can enable live-cell imaging to indicate effective payload delivery, increasing the potential of identifying clinically viable ADC leads.

Polyethylene glycol and similar variants have driven innovative research for therapies. However, the continued use of PEG poses significant drawbacks. Explore those concerns here.

The pros and cons of soluble and insoluble processes: isolating, solubilizing, properly refolding, and strategies to improve the performance of IB processes.

There are many factors to consider when tasked with acquiring the equipment needed to run a pharma facility. Being aware of every up-front cost is a must when determining optimal equipment ownership.

Review our work to establish a protocol for culturing Vero cells in serum-free medium on the Corning CellCube System, a compact and scalable method for mass culture of attachment-dependent cells.