ARTICLES BY MATTHEW PILLAR

  • Where Oncology Drug Discovery Goes Next
    5/30/2023

    AbbVie Bay Area Site Head and VP of Oncology Discovery Research Steve Davidsen, Ph.D. lays out the primary challenges to pushing forward in areas of high, unmet oncological need: accelerating discovery to shorten the time to patient impact and identifying optimal patients for a given mechanism of action or molecule.

  • Immunome’s Platform Partnership Potential
    5/16/2023

    Immunome’s discovery engine caught AbbVie’s eye, nabbing the biotech a transformative deal. CEO Purnanand Sarma, Ph.D. and CFO Corleen Roche take us behind the scenes.

  • Active ADC Space Challenges Development Strategies
    5/15/2023

    Payload and linker technology advances have contributed to an explosion in antibody-drug conjugate development in recent years, amd the funding has followed. But, while the face value of ADC activity represents a bright spot in an otherwise sluggish biotech investment environment, the challenges of doing business in a hotly competitive market are playing out.

  • Anatomy Of A Biopharma VC Deal
    4/20/2023

    Why does a venture capitalist choose to fund a biopharma company? What prompts them to choose not to? And why should (or shouldn't) a biopharma company take a VC's money?

  • Topical Biologics In Ophthalmology?
    3/21/2023

    A recent clinical study of an eyedrop formulated with Grifols’ Immunoglobulin-based Flebogamma DIF offers cause for optimism among multiple stakeholders. It could become the first-approved topically administered biologic therapy for dry eye disease. 

  • AAV Manufacturing Field: An Interactive Look
    3/17/2023

    Mapping the adeno-associated virus (AAV) therapeutic space gives us a glimpse into indication priorities for gene therapy, and a look at whose got their fingers in which partners’ pots. Check out this interactive graphic from DeciBio Principal Carl Schoellhammer, Ph.D. It's not only instructive, its kind of therapeutic to play with. 

  • Cashing In On Biopharma Collaboration
    3/14/2023

    How does a biopharma business that’s potentially years away from its first shot at therapeutic sales revenue thrive in a high-inflation, high-interest, supply-constrained business environment?

  • What’s In A “Biopharma” Name?
    2/23/2023

    As exciting new modalities, hybrids, and conjugates blur therapeutic lines, let’s not forget what “bio” means, how biologic therapeutics are distinguished, and why they were delineated as such in the first place. Make sure you're not a BINO (Bio In Name Only) when you’re naming your “biotech.”

  • FDA Submission Automation: Coming To A Cloud Near You
    2/15/2023

    The FDA is laying the groundwork for standardized, cloud-based electronic submission standards via an initiative that leverages data automation and artificial intelligence. What will it mean to biopharma filers?

  • Bench To Boardroom: A Scientist-Turned-CEO’s Journey
    2/13/2023

    Novadip Biosciences CEO Denis Dufrane, M.D., Ph.D. got a crash course in biopharma leadership, but not before he left cell therapy research on his own timeframe. He sat down with Bioprocess Online to tell us what he learned.

  • Antibody-Drug Conjugates: Increasing Investment In R&D And Partnerhip
    2/1/2023

    DeciBio’s Antibody-Drug Conjugates 2023 Industry Survey points to progress in ADC development. Respondents anticipate lower regulatory, financial, and R&D barriers as the technology matures. Senior Life Science Expert Joe Daccache, Ph.D. gave us an insider's look at the numbers.

  • What's True Of Mice ≠ What's True Of Men
    1/27/2023

    After losing his mother to pancreatic cancer, entrepreneur Alex Blyth launched an immuno-oncology company that’s developing a novel allogeneic cell therapy. The company, LIfT BioSciences, recently received a shot in the arm when it was accepted into Johnson & Johnson Innovation’s JLABS network.

  • Can JP Morgan Help San Francisco?
    1/25/2023

    My first in-person JP Morgan Healthcare Conference was great for business. It also left me wondering what the world's toniest healthcare conference is doing for the health of its ailing host city.

  • A Personal Case For Drug Repurposing
    1/20/2023

    Amidst the dealmaking and spectacle of the 41st Annual JP Morgan Healthcare Conference, a bright and personal light was cast on the value of a different kind of collaboration: drug repurposing. There’s a deep vein of patient benefit sitting on pharmacy shelves, and Michael Fajgenbaum, M.D. wants to tap it. 

  • 60 Minutes To IND Success
    1/6/2023

    On 1/24/23, Daniela Drago, Ph.D. and Kati Abraham will join us for the discussion, IND Success: Navigate Through The Regulatory Gray, and I hope you do, too. We’ll talk through reasons for clinical holds, offer tips for avoiding and addressing them, and share best practices on ensuring smooth submissions on your journey from development to the clinic.

  • Big Bio Breeds Startup Leadership
    12/27/2022

    Richard Francis’ arrival at Purespring in 2021 was indicative of a longer-term trend in the biopharma space that’s inciting a bit of a talent exodus from Big Pharma to emerging bio. While he's now returning to his big pharma generics roots, here's what he looked for in a startup leadership opportunity.

  • Snake Oil Or Slippery CEO?
    12/22/2022

    Nader Pourhassan was just charged with a whole bunch of crimes. At the nucleus of the charges sits Pourhassan’s overzealous—and as it turns out, illegal—oversell of leronlimab, the monoclonal antibody he hyped as an HIV and COVID-19 therapeutic panacea when he was CEO at Cytodyn.

  • Inside The Altavant/Enzyvant Self-Made Merger
    12/21/2022

    Prior to their merger, Enzyvant and Altavant didn’t have much in common beyond their suffix and their CEO. That CEO is Bill Symonds, Pharm.D., the architect of the merger whose history with the "vants" runs deep. Here, Dr. Symonds shares the company’s strategy and the implications of the combination. 

  • From Racecars To Regenerative Medicine
    12/14/2022

    Find out what inspired a mechanical engineer, a U.S. Marine veteran, and a racecar driver to launch a regenerative medicine company manufacturing perinatal tissue allografts and get its products to market at breakneck speed.

  • Data Confidence Drives Clinical, Financial Perseverance
    12/7/2022

    Under the leadership of Mai-Britt Zocca, Ph.D., IO Biotech raised a $150 million Series B during a pandemic to move forward with a target that's seen its fair share of failure. To get there, the clinical stage biopharma leaned hard into its data differentiators.

  • Venture Philanthropy Launches Biotech From Within
    11/23/2022

    There are more than 260 genes known to cause inherited retinal diseases, and Opus Genetics’ discovery and development work is leaving none of those stones unturned. The company’s genesis story is unique, though replicable and representative of a greater trend among emerging biopharmaceutical companies.

  • Computational Biology Speeds The Path To Clinical Studies
    11/17/2022

    Computer-aided 3D modeling enables quick assessment of previously undiscovered protein binding sites and helps scientists at Gain Therapeutics marry them to the correct therapeutic molecules. Find out how the approach works, and its role in accelerating the company’s path to the clinic in Parkinson’s disease. 

  • From Sales To The C-Suite Of Pioneering Gene Therapy
    11/15/2022

    AviadoBio is building a pipeline of investigational gene therapies for neurodegenerative diseases. Its lead preclinical candidate is AVB-101 for GRN frontotemporal dementia (FTD-GRN). It’s an intra-thalamic gene supplementation therapy, and as it heads to clinical trials, it's being overseen by a ladder climber who's seen it all.

  • Where Biotech Business Nuance Isn’t Lost
    11/14/2022

    You read, you watch, you listen, you travel to conferences and events, and you learn from all of it, but none of those are the leading source of information for those who seek it. What medium do most biopharma leaders actively seek when it’s learning they’re yearning? Conversation.

  • Are Immunotherapeutic Vaccines The Next Biologic Revolution?
    11/9/2022

    Vaxxinity, small as it may be on the greater pharma landscape, is carving out positions as innovator, disruptor, and leader in what CEO Mei Mei Hu, J.D. refers to as the third biologic revolution. Here, she shares Vaxxinity's position on immunotherapeutic vaccines in the context of traditional vaccines and biologics and offers insight into the company's unique culture. 

mattpillar-aboutus

Matthew Pillar

Matthew Pillar is chief editor at Bioprocess Online. He's spent the past 20 years covering tech-centric industries as they’ve navigated AI, machine learning, IoT, and other emerging technologies. His chief and executive editorial experience includes tenures with Software Executive, Channel Executive, Business Solutions and ISR magazines, where he routinely interviewed international technology builders and influencers. Pillar has spoken on emerging technologies and their implications at major events for leading tech vendors including NetSuite, Oracle, SAP, and others.

Connect with Pillar on LinkedIn at linkedin.com/in/matthewpillar/