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DOWNSTREAM PROCESSING

59:51 GettyImages-597971944-viral-vector-AAV-adeno-associated-virus
Upstream To Downstream: A Comprehensive Approach To AAV Production

How can you face the challenges of AAV production, scale up your AAV manufacturing effectively, and enhance the recovery and purity in your downstream processing.

20:10 An Innovative Approach To High Aggregate Challenges
An Innovative Approach To High Aggregate Challenges

In this webinar, hear from a technical specialist on addressing the challenges with antibody aggregates and process related impurity removal using a new high performance chromatography resins

1:15:45 AAV Purification
AAV Purification: Solving Downstream Challenges

In this roundtable discussion, a trio of distinguished experts in AAV purification and process development share their expertise and best practices in tackling and solving downstream challenges.

6:37 24_06_BPOL_1280x720_Seg05
Process Intensification Development Challenges At AZ and AbbVie

In this segment of the Bioprocess Online Live event Bioprocess Intensification In The Real World, panelists respond to audience questions about the challenges they’ve encountered while developing process intensification strategies.

5:17 BPI Interviews Purification And Pharma Analytics Leader
BPI Interviews Purification And Pharma Analytics Leader

Jean Luo, VP of Purification and Pharma Analytics, discusses innovations in bioprocessing, including the development of dPCR assays, lentiviral titer systems, chromatography resins, and supply chain.

18:11 DoE Methodology For Downstream Purification Of pDNA Of IEX Resins
DoE Methodology For Downstream Purification Of pDNA Of IEX Resins

Learn a systematic approach using Design of Experiment to optimize plasmid DNA purification. See how anion exchange resins are evaluated to enhance dynamic binding capacity and process efficiency.

4:13 24_08_BPOL_1280x720_Seg04
Addressing Post-Translational Modifications In Novel Protein Therapeutics

Meinhard Hasslacher, Ph.D., Head of CMC at SOTIO Biotech, addresses an audience question on conjugation efficiencies in this segment of the Bioprocess Online Live event Early Process Considerations For Novel Protein Therapeutics. From there, we move on to an audience-led ...

2:16 Fill Finish Solution
Maximize Your Drug Product Recovery With A Complete Fill Finish Solution

Discover how to maximize drug product recovery with an end-to-end fill-finish solution. Get excellent integrity assurance and exceptional lead times for your critical processes.

57:03 Chromatography GettyImages-1392302602
Speed Up Process Development With HTS Tools For Affinity Chromatography

High Throughput Screening (HTS) chromatography tools can accelerate process development and reduce material usage. Learn about a solution that addresses challenges with their use in new modalities.

0:40 Explore The Resin Selection Tool
Simplify Your Process Of Choosing An Optimal Resin

Discover how to address evolving biotherapeutic purification challenges with a diverse resin portfolio and an intuitive Resin Selection Tool designed to streamline workflows and enhance production efficiency.

57:14 Driving The Expansion Of mRNA Into The Therapeutic Sphere
Driving The Expansion Of mRNA Into The Therapeutic Sphere

Discover the next wave of mRNA therapeutics and how emerging technologies are solving key challenges in downstream processing and analysis to enhance both safety and efficacy.

54:41 advances in flow-through technology
Advances In Flow-Through Technology To Enhance mAb Polishing

Walk through three case studies that illustrate how novel chromatographic tools can improve the purification process for complex therapeutics by reducing aggregates and HCPs and effectively clearing retroviruses.

33:13 Purification Tools To Address Low Yield Challenges With Protein A
Purification Tools To Address Low Yield Challenges With Protein A

Discover new affinity chromatography resins for engineered modalities. Learn how they boost yield and reduce aggregation with high-specificity binding and mild elution. Ideal for purifying novel mAbs, BsAbs, and mAb fragments.

0:20 Explore The Analytics Knowledge Hub
Explore The Analytics Knowledge Hub

Discover smarter solutions with the new Analytics Knowledge Hub that provides articles, webinars, e-books, and infographics designed to enhance and streamline your bioprocess workflow.

3:59 24_06_BPOL_1280x720_Seg08
What's Next For Bioprocess Intensification?

Experts speaking on Bioprocess Intensification In The Real World wrap up the Bioprocess Online Live event with parting shots and reflections on the current state of process intensification and what the future holds.

1:02 Process Liquids And Buffers Offering
Process Liquids And Buffers Offering

Whether you are a researcher, scientist, or industry professional, this video will provide valuable insights into our large volume liquids manufacturing capabilities.

3:46 Thermo Screen splash
Singapore Single-Use Site Capacity Expansion

Thermo Fisher Scientific is expanding our single-use manufacturing network globally, an expansion site closer to Asia Pacific region

4:11 24_06_BPOL_1280x720_Seg02
What Bioprocessing Bottlenecks Does Process Intensification Address?

Supply chains, consumables, and data are identified as three of the management challenges that intensified processes and process automation technology (PAT) are addressing at AbbVie and AstraZeneca.

1:01:01 Advancing Gene Therapy Development With A Multi-Serotype AAV Resin
Advancing Gene Therapy Development With A Multi-Serotype AAV Resin

In this webinar, leading CDMO ABL and Thermo Fisher will share data on implementation of the POROS™ CaptureSelect™ AAVX affinity resin into such an AAV purification platform, including its performance in purifying several serotypes.

0:42 Bioprocessing Downstream Calculators
Simplify Your Downstream Calculations With Bioprocessing Downstream Calculators

Simplify complex biopharma downstream processing tasks using a suite of powerful, web-based calculators designed to streamline workflows and automate intricate mathematical modeling.

2:41 Thermo Dynachrom
What Is The DynaChromâ„¢ Single-Use Chromatography System?

This chromatography system offers a flexible solution, paired with an advanced software platform, allowing easy integration with downstream process automation.

1:48 Setup Made Simple With The BioTitan Retention Device
Setup Made Simple With The BioTitan Retention Device

Find out how quick and simple it is to set up an assembly secured with the Thermo Scientific BioTitan Retention Device.

3:08 HyPerforma DS 300 Single-Use Mixer Overview
HyPerforma DS 300 Single-Use Mixer Overview

Watch this video to learn more about the Thermo Scientific HyPerforma Single-Use Mixer DS 300. This Modular mixing system offers a cost-effective, docking station-style mixing platform with multiple mixing-volume options.

3:32 Laurens_Sierkstra
Tailoring Purification Solutions To Address Customer Challenges

Developing purification products for novel biotherapeutics requires close customer collaboration to ensure the tools do the job. Hear how these partnerships drive targeted innovation.

5:02 Thermo Fisher Scientific Suzhou, China Manufacturing Site Capabilities
Thermo Fisher Scientific Suzhou, China Manufacturing Site Capabilities

Watch this video to learn more about this manufacturing site capabilities, quality management systems, PPI implementation, product expansion, assurance of supply and lead times.

1:01 Affinity Resins Overview
Affinity Resins Overview

We have developed a unique portfolio of affinity resins to help you develop biosimilars, biobetters, and other types of recombinant proteins. These affinity resins can be used for clinical and commercial production.

50:01 mAbs GettyImages-1441786721
Accelerating mAb Process Development In The Growing Therapeutics Market

The market for mAbs and mAb variants is growing rapidly. Explore the latest strategies and advancements in early stage mAb up- and downstream process development.

2:39 resdnaseq workflow
ResDNASEQ Workflow Solution

Explore the Applied Biosystems resDNASEQ workflow solutions. Starting with the sample preparation kit, to purification, quantitating residual host-cell DNA, and analyzing resDNASEQ assays.

6:59 Thermo Fisher Scientific Large Volume Liquid Expansion
Thermo Fisher Scientific Large Volume Liquid Expansion

Take an insightful look into the expansion of the large volume liquids manufacturing site at the Grand Island facility, highlighting the various stages of the manufacturing process and the capabilities it offers to support the bioprocessing industry.

34:34 Beyond Standard Protein A Resin
Beyond Standard Protein A Resin

In this study, mAbCapture C affinity resin has been compared with a Protein A resin used in a DSP platform, showing a higher dynamic binding capacity while keeping the product’s critical quality attributes within acceptable limits.