DOWNSTREAM PROCESSING
Advancing The Purification Of VSV-G Pseudotyped Lentiviral Vector
Discover new strategies to overcome lentiviral purification challenges with a scalable approach that maintains viral infectivity through gentle processing conditions.
Thermo Fisher Scientific Single-Use Global Manufacturing Network
We have implemented a multi-tier strategy to improve the resiliency of our supply chain and created the largest networked single-use manufacturing organization in the world.
Addressing Post-Translational Modifications In Novel Protein Therapeutics
Meinhard Hasslacher, Ph.D., Head of CMC at SOTIO Biotech, addresses an audience question on conjugation efficiencies in this segment of the Bioprocess Online Live event Early Process Considerations For Novel Protein Therapeutics. From there, we move on to an audience-led ...
CaptureSelect Affinity Chromatography
30-second video sharing a visualization of our CaptureSelect affinity chromatography capability. The target protein binds with VHH molecules immobilized on the chromatography beads, non-target proteins are removed, and the eluted fraction contains a high yield of pur...
Beyond Standard Protein A Resin
In this study, mAbCapture C affinity resin has been compared with a Protein A resin used in a DSP platform, showing a higher dynamic binding capacity while keeping the product’s critical quality attributes within acceptable limits.
CaptureSelect™ Technology - Powerful Affinity For More Streamlined Purification
Replace inefficient chromatographic steps with high-specificity affinity ligands to streamline downstream processing. This approach simplifies workflows and protects sensitive biomolecules.
Rethinking Sustainability In Bioprocessing
Discover how sustainability is transforming bioprocessing through innovative single-use technologies that help reduce environmental impact and support responsible, forward-thinking biomanufacturing.
Advancing Gene Therapy Development With A Multi-Serotype AAV Resin
In this webinar, leading CDMO ABL and Thermo Fisher will share data on implementation of the POROS™ CaptureSelect™ AAVX affinity resin into such an AAV purification platform, including its performance in purifying several serotypes.
The Way Forward: Supply Chain Solutions
Learn how to build a resilient supply chain to navigate today's complex environment. Expert speakers share insights on optimization, innovation, and strategic planning to meet evolving market conditions.
Accelerating mAb Process Development In The Growing Therapeutics Market
The market for mAbs and mAb variants is growing rapidly. Explore the latest strategies and advancements in early stage mAb up- and downstream process development.
What's Next For Bioprocess Intensification?
Experts speaking on Bioprocess Intensification In The Real World wrap up the Bioprocess Online Live event with parting shots and reflections on the current state of process intensification and what the future holds.
What Is The DynaChrom™ Single-Use Chromatography System?
This chromatography system offers a flexible solution, paired with an advanced software platform, allowing easy integration with downstream process automation.
Efficient AAV Purification With AAVx And AAV9 Magnetic Beads
Explore an alternative to chromatographic affinity capture that eliminates the need for universal nuclease treatment by utilizing magnetic beads with ligands specific to AAV.
Upstream To Downstream: A Comprehensive Approach To AAV Production
How can you face the challenges of AAV production, scale up your AAV manufacturing effectively, and enhance the recovery and purity in your downstream processing.
Process Liquids And Buffers Offering
Whether you are a researcher, scientist, or industry professional, this video will provide valuable insights into our large volume liquids manufacturing capabilities.
Ingress Leak Test For Bioprocess Containers
When a visual inspection with magnification isn't enough, the IPA ingress test can definitively confirm a leak. Learn how to perform this critical quality test.
Enhancing AAV Purification In Gene Therapy Manufacturing
Review chromatography solutions for purifying multiple AAV serotypes, with specialists’ insights on bioprocessing and downstream optimization.
Efficient Downstream Processing Of Antibody-Based Therapeutics – A CDMO Perspective
Discover efficient downstream processing strategies for antibody-based therapeutics. Explore key considerations and trade-offs in purity, yield, speed, and cost, from a CDMO perspective.
Three Novel Protein Therapeutic Worldviews
In this segment of the Bioprocess Online Live event Early Process Considerations For Novel Protein Therapeutics, we meet panelists who share their topline perspectives on developing complex, novel protein therapeutics.
Manufacturing Friendly Aggregate Clearance In Downstream Processing
In this webinar, results are shared from the evaluation and preliminary optimization of a mixed-mode chromatography unit operation designed for aggregate removal in flow-through mode using a high-throughput POROS resin with immobilized caprylic acid.
Bioprocessing Equipment And Automation Product Portfolio Overview
Accelerate biotherapeutic development with innovative bioprocessing equipment and automation solutions that feature single-use mixers, bioreactors, and more to streamline workflows and speed products to market.
mAb Up- And Downstream Process Intensification Strategies
Discover how to reduce monoclonal antibody (mAb) manufacturing time and costs through process intensification. Learn about continuous perfusion, ultrahigh cell density banks, and more.
Developing A 2-Step Chromatographic Process For The Purification Of AAV Vectors
POROS CaptureSelect AAVX and POROS 50 HQ were tested for capture and polishing, respectively, of AAV2, AAV9 and a novel engineered capsid to achieve vectors with high purity and significant empty: full ratio improvement.
Singapore Single-Use Site Capacity Expansion
Thermo Fisher Scientific is expanding our single-use manufacturing network globally, an expansion site closer to Asia Pacific region
Process Development With Chromatography Resins And Expert Support
Watch a Senior Product Manager discuss insights on emerging challenges and advanced downstream purification solutions for biologic therapeutics with chromatography resins, expert knowledge, and dedicated support.
Affinity Resins Overview
We have developed a unique portfolio of affinity resins to help you develop biosimilars, biobetters, and other types of recombinant proteins. These affinity resins can be used for clinical and commercial production.
HyPerforma DS 300 Single-Use Mixer Overview
Watch this video to learn more about the Thermo Scientific HyPerforma Single-Use Mixer DS 300. This Modular mixing system offers a cost-effective, docking station-style mixing platform with multiple mixing-volume options.
Quality Roundtable: Optimizing Biologics Manufacturing Processes With Raw Materials
Improve your commercial manufacturing process with advice from regulatory and raw materials experts on the development journey from pre-clinical to licensure.
Key Attributes To Monitor During Cell Line Development Of Complex Proteins
In this segment of the Bioprocess Online Live event Early Process Considerations For Novel Protein Therapeutics, panelists discuss key attributes to monitor during cell line development processes.
Enhanced Chromatography Resins For Faster, More Efficient Purification
Learn from an industry veteran about the evolution of protein purification, from early equipment to modern, agile solutions, emphasizing continuous improvement and customer-centric approaches.