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DOWNSTREAM PROCESSING

1:01 Affinity Resins Overview
Affinity Resins Overview

We have developed a unique portfolio of affinity resins to help you develop biosimilars, biobetters, and other types of recombinant proteins. These affinity resins can be used for clinical and commercial production.

26:21 mRNA-Based Therapeutics Development Through Efficient mRNA Purification
mRNA-Based Therapeutics Development Through Efficient mRNA Purification

Discover how a novel affinity resin simplifies and maximizes the purification of mRNA therapeutics. Learn about the scalable technique vital for commercial manufacturing.

5:04 Thermo Fisher Scientific Customer Testimonial - Libbs
Thermo Fisher Scientific Customer Testimonial - Libbs

An overview of Libbs product portfolio and how they benefit from Thermo Fisher Scientific services.

3:59 24_06_BPOL_1280x720_Seg08
What's Next For Bioprocess Intensification?

Experts speaking on Bioprocess Intensification In The Real World wrap up the Bioprocess Online Live event with parting shots and reflections on the current state of process intensification and what the future holds.

18:02 BIO-EXPO Live
Enhancing Aseptic Fill-Finish Processes

Achieve exceptional product recovery and sterility. Learn about high-integrity surge bags, advanced leak detection, and flexible design options for your fill-finish applications.

1:15:45 AAV Purification
AAV Purification: Solving Downstream Challenges

In this roundtable discussion, a trio of distinguished experts in AAV purification and process development share their expertise and best practices in tackling and solving downstream challenges.

1:02 Process Liquids And Buffers Offering
Process Liquids And Buffers Offering

Whether you are a researcher, scientist, or industry professional, this video will provide valuable insights into our large volume liquids manufacturing capabilities.

7:03 24_08_BPOL_1280x720_Seg03
Key Attributes To Monitor During Cell Line Development Of Complex Proteins

In this segment of the Bioprocess Online Live event Early Process Considerations For Novel Protein Therapeutics, panelists discuss key attributes to monitor during cell line development processes.

27:51 Thermo Roundtable screenshot
Quality Roundtable: Optimizing Biologics Manufacturing Processes With Raw Materials

Improve your commercial manufacturing process with advice from regulatory and raw materials experts on the development journey from pre-clinical to licensure.

4:11 24_06_BPOL_1280x720_Seg02
What Bioprocessing Bottlenecks Does Process Intensification Address?

Supply chains, consumables, and data are identified as three of the management challenges that intensified processes and process automation technology (PAT) are addressing at AbbVie and AstraZeneca.

4:03 Andy Davies
Enhanced Chromatography Resins For Faster, More Efficient Purification

Learn from an industry veteran about the evolution of protein purification, from early equipment to modern, agile solutions, emphasizing continuous improvement and customer-centric approaches.

34:22 Considerations For Affinity Capture In An AAV Platform Downstream Process
Considerations For Affinity Capture In An AAV Platform Downstream Process

This presentation explores the considerations when evaluating a platform affinity capture step for the purification of AAV vectors. Specificity, binding capacity, purity, yield, scalability and reusability are parameters that will be addressed.

1:00:49 Developing A 2-Step Chromatographic Process
Developing A 2-Step Chromatographic Process For The Purification Of AAV Vectors

POROS CaptureSelect AAVX and POROS 50 HQ were tested for capture and polishing, respectively, of AAV2, AAV9 and a novel engineered capsid to achieve vectors with high purity and significant empty: full ratio improvement.

33:07 Manufacturing Friendly Aggregate Clearance In Downstream Processing
Manufacturing Friendly Aggregate Clearance In Downstream Processing

In this webinar, results are shared from the evaluation and preliminary optimization of a mixed-mode chromatography unit operation designed for aggregate removal in flow-through mode using a high-throughput POROS resin with immobilized caprylic acid.

2:39 resdnaseq workflow
ResDNASEQ Workflow Solution

Explore the Applied Biosystems resDNASEQ workflow solutions. Starting with the sample preparation kit, to purification, quantitating residual host-cell DNA, and analyzing resDNASEQ assays.

34:34 Beyond Standard Protein A Resin
Beyond Standard Protein A Resin

In this study, mAbCapture C affinity resin has been compared with a Protein A resin used in a DSP platform, showing a higher dynamic binding capacity while keeping the product’s critical quality attributes within acceptable limits.

0:42 Bioprocessing Downstream Calculators
Simplify Your Downstream Calculations With Bioprocessing Downstream Calculators

Simplify complex biopharma downstream processing tasks using a suite of powerful, web-based calculators designed to streamline workflows and automate intricate mathematical modeling.

8:56 24_06_BPOL_1280x720_Seg07
Considerations In Continuous Chromatography

In this segment of the Bioprocess Online Live event Bioprocess Intensification In The Real World, our presenters discuss considerations for continuous versus batch chromatography and compare notes on the approaches at their respective organizations.

5:02 Thermo Fisher Scientific Suzhou, China Manufacturing Site Capabilities
Thermo Fisher Scientific Suzhou, China Manufacturing Site Capabilities

Watch this video to learn more about this manufacturing site capabilities, quality management systems, PPI implementation, product expansion, assurance of supply and lead times.

1:10 Nalgene Ultralow Particulate Bottles And Carboys
Ultralow Particulate Bottles And Carboys: Where Being Particular About Particulates Is Critical

Optimize your operations with ready-to-use, meticulously prepared containers. Learn how our commitment to cleanliness reduces risks and supports your most critical requirements.

56:12 Thermo Fisher - Downstream Processing webinar
Tools For Efficient Downstream Processing Of Antibody-Based Therapeutics

Watch and discover how to effectively utilize chromatography tools for improved purification of therapeutic monoclonal antibodies and antibody derivatives.

48:22 Advancing Vaccine Development
Advancing Vaccine Development With Novel Chromatography Solutions & Quality Testing

Learn more on novel chromatography solutions that can help improve the downstream processes of different vaccine types such as mRNA, recombinant proteins, and Virus-Like Particles (VLPs).

6:59 Thermo Fisher Scientific Large Volume Liquid Expansion
Thermo Fisher Scientific Large Volume Liquid Expansion

Take an insightful look into the expansion of the large volume liquids manufacturing site at the Grand Island facility, highlighting the various stages of the manufacturing process and the capabilities it offers to support the bioprocessing industry.

3:26 captureselect technology
CaptureSelectâ„¢ Technology - Powerful Affinity For More Streamlined Purification

Replace inefficient chromatographic steps with high-specificity affinity ligands to streamline downstream processing. This approach simplifies workflows and protects sensitive biomolecules.

33:13 Purification Tools To Address Low Yield Challenges With Protein A
Purification Tools To Address Low Yield Challenges With Protein A

Discover new affinity chromatography resins for engineered modalities. Learn how they boost yield and reduce aggregation with high-specificity binding and mild elution. Ideal for purifying novel mAbs, BsAbs, and mAb fragments.

7:10 24_06_BPOL_1280x720_Seg06
What Analytics Drive Process Intensification?

Bioprocess Online Live panelists discuss the most fundamental analytics that inform and enable process intensification strategies in this segment of Bioprocess Intensification In The Real World.

13:33 24_06_BPOL_1280x720_Seg04
Process Intensification Audience Q&A

Our panelists take audience questions on process intensification lessons learned from other industries.

3:47 Mary Fitzgibbon
Ensuring Quality, Driving Customer Confidence

How does quality assurance help drive scientific progress? A 30-year veteran shares her story of supporting customer needs and the development of groundbreaking new therapeutics.

1:05:00 GettyImages-1181190018 supply chain pharma, bio
The Way Forward: Supply Chain Solutions

Learn how to build a resilient supply chain to navigate today's complex environment. Expert speakers share insights on optimization, innovation, and strategic planning to meet evolving market conditions.

17:22 Bio-Expo Live
Process Development With Chromatography Resins And Expert Support

Watch a Senior Product Manager discuss insights on emerging challenges and advanced downstream purification solutions for biologic therapeutics with chromatography resins, expert knowledge, and dedicated support.