Purification Tools To Address Low Yield Challenges With Protein A

Traditional Protein A chromatography often struggles to purify novel modalities like bispecific antibodies and mAb fragments, leading to poor yields and complex byproducts. To address this, new affinity chromatography resins have been developed to target different antibody-subdomain regions. This approach uses high specificity and mild elution conditions to significantly increase yield, reduce aggregation, and improve overall purity.

In this webinar, we explore this next-generation technology and its impact on manufacturing engineered antibodies. Watch the video to see how to optimize your downstream process.