Upstream Manufacturing Solutions

  1. 100% Animal-Free Production And Control 6/9/2026

    See animal-free peptones and hydrolysates enabling consistent, scalable cell culture and fermentation, with variability reduction, regulatory support, and customizable manufacturing solutions.

  2. GPEx® Lightning: Stable Cell Line Development For Complex Biologics 6/5/2026

    GPEx® Lightning delivers stable cell pools in 25 days, titers exceeding 15g/L for mAbs and 11g/L for bispecifics, and 60+ generations of stability — compressing timelines by 6–12 weeks.

  3. CHO Transient Production (TunaCHO® Process) 6/5/2026

    CHO cells have been the workhorse for protein and antibody manufacturing. The major advantages of CHO include robust growth, hardiness in suspension culture, stellar protein production and secretion, and a long track record.

  4. HEK293 Transient Production (Tuna293® Process) 6/5/2026

    HEK293 cells have been the most popular mammalian transient production platform. The primary advantage of HEK293 cells is transfection efficiency.

  5. Mammalian High-Throughput Production 6/5/2026

    The demand for high-throughput antibodies has exponentially increased over the last couple of years and has rapidly accelerated the antibody screening process.

  6. Madison: Clinical, Commercial Drug Substance Development 6/2/2026

    Catalent Madison offers gene-to-GMP drug substance in 8 months via GPEx Lightning CHO cell lines, hitting 15+ g/L, backed by 24 approved products and 5 GMP trains up to 4,000 L.

  7. CHO Residual DNA Quantitation 5/29/2026

    Highly sensitive detection of trace DNA impurities supports safer manufacturing. Combining rapid workflows, strong specificity, and reliable recovery from complex samples enables confident monitoring.

  8. Leading The Way In Rapid Quantitation Of Host Cell DNA 5/29/2026

    Accurate, high-sensitivity quantitation of residual host cell DNA becomes faster and more consistent with integrated qPCR, automated prep, and broad assay coverage—helping streamline workflows.

  9. Increase Cell Culture Yield Without Increasing Aggregation 5/22/2026

    Designed for CHO cell culture processes, the HyClone™ glycan supplement enhances galactosylation and maintains stable culture performance.

  10. Used 1,200 Liter Precision Stainless Reactor 5/20/2026

    Used 1200 liter Precision Stainless reactor, Hastelloy C276 construction, approximately 52" diameter x 33" straight side, dish top and bottom, rated 45 psi and full vacuum at 350 f internal, jacketed for 100 psi and full vacuum at 350 f, top entering off center .5 hp Lightnin agitator drive, 90 volt dc, 18" top manway, 1.5" bottom outlet, with forklift access, serial# 211929-3, national board# 9863, built 2002.