Insights On Polish & Viral Filtration

  1. TFF Cassettes With 100 kDa Membranes For RNA And LNP Applications 7/3/2024

    This study showcases the performance of regenerated cellulose flat sheet membranes with a 100 kDa molecular weight cutoff for UF/DF of RNA molecules by TFF.

  2. Accelerating Bulk Harvest Release Testing With A PCR-Based Solution 7/3/2024

    Adventitious agent testing is frequently a bottleneck in downstream processing. Discover a PCR-based solution for manufacturing processes using CHO cells and animal origin-free components.

  3. High-Performance Extraction And Quantitation Of Host-Cell Residual DNA 6/19/2024

    This study presents a high-efficiency method for extracting and quantifying residual DNA from host cells using a semi-automated, high-throughput workflow.

  4. Bispecific Antibodies Unleashed 5/16/2024

    Explore how leveraging expert CDMO partnerships can streamline the development process and enhance the efficacy of your bispecific antibody therapies.

  5. Developing A Large-Scale Tangential Flow Filtration Process 5/13/2024

    Discover a process that can be modified to fit your downstream process and serves as a complete solution for concentration and diafiltration.

  6. Sterilizing Grade Filter Performance With Biologic Drugs 3/11/2024

    Examine the throughput performance of sterilizing grade filters across moderate-to-high concentrations of mAbs and immunoglobulins as well as how filter selection can impact your process.

  7. Viscosity Reducing Excipients For Filtration Process Improvement 1/2/2024

    We demonstrate two filtration methods evaluating the effect of the excipients in the Viscosity Reduction Platform on ultrafiltration processes used to produce a highly concentrated mAb formulation.

  8. Intensifying A mAb Polishing Platform 11/29/2023

    We demonstrate how a mAb purification batch process can be converted into a stepwise intensified batch process, successfully eliminating intermediate steps and achieving over 13% cost reductions.

  9. Developing A HIC Polishing Step For The Removal Of mAb Aggregates 9/28/2023

    Learn in-depth about the development of a flow-through polishing step that employs hydrophobic interaction chromatography for the elimination of monoclonal antibody aggregates.

  10. Performance Of A Fully Automated, Single-Use TFF System In ADC Processes 3/21/2023

    Antibody-drug conjugates (ADCs) represent a significant area of growth in the biopharmaceutical industry. Explore the capabilities of a highly scalable, productive platform to streamline ADC production processes.