Downstream Processing White Papers and Case Studies
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Discussion Of Vial Closures And Stoppering Force In Pilot Freeze-Dryers
To answer the often asked question "Can my system stopper a full tray of the vials and stoppers I have selected?,", it is important to be able to recognize the force needed for your particular container-closure system and to compare that to the stoppering pressure specification provided by the freeze dryer manufacturer. By Leslie Mather
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Proven Long Life Lasers™ In Optical Particle Counters
12/1/2011
Optical particle counters (OPC) utilize light illumination and extinction to determine the presence, size, number and/or concentration of particles. Particles are typically suspended in a fluid or air, which flow through the volume that is illuminated and viewed by the detection system.
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Meeting BioPharma Needs For Lower Operating Cost And Faster Time To Market
11/28/2012
Broad adoption awaits fully scalable GMP systems, improved and less costly disposables, better analytics, greater process automation and low-shear mixing.
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Determination Of kLa Values Of Single-Use Bioreactors
8/3/2016
Because single use bioreactors offered by manufacturers vary in parameters critical for oxygen transfer, they are often not comparable to each other and to conventional glass and stainless steel vessels.
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How To Characterize Multimodal Samples Using Particle Characterization Equipment
This application note will discuss the topic of size resolution in particle characterization and advantages and disadvantages of various techniques.
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One Bioreactor System For The Bioproduction Of 2 High-Demand Chemicals
7/28/2016
A large variety of chemicals can be efficiently produced by microbial fermentation. They are used in a multitude of applications; for example, as biofuels, building blocks for polymers, food supplements, and ingredients for cosmetics. To be profitable, fermentation processes have to deliver the desired end product at a high yield and a high titer.
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White Paper: Computrac® Moisture Analysis Made Simple
8/10/2011
When people aren’t feeling their best they often turn to medicine for relief from the symptoms that are associated with being ill. The public trusts that the products by pharmaceutical companies will not only make them feel better but will also not have harmful side effects.
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Biomanufacturing Complexity
12/22/2011
This white paper addresses one of the most serious challenges facing biomanufacturing professionals today - how to understand and then deal with the extreme complexity associated with biotechnology manufacturing.
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Considerations For The Development Of Stable Cell Lines From Parental Lines
9/30/2011
Quality standards are often difficult to properly anticipate across today’s global regulatory environments. In recent years, quality expectations have increased due to public demand and to government regulation. This article explores some important considerations when determining quality standards for parental cell lines.
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USP <787> Small Volume Testing With Liquid Particle Counters
By their very nature, biological therapeutics are not only expensive to manufacture but are often produced in small volumes.