ABOUT ROOSTERBIO
RoosterBio accelerates human mesenchymal stem/stromal cell (hMSC) and extracellular vesicle (EV) product and process development to fuel the rapid commercialization of scalable regenerative cures. Our high-quality hMSCs, bioprocess media, genetic engineering tools, and EV production solutions are paired with expert bioprocessing knowledge to progress therapeutic developers from concept to first-in-human testing and commercial manufacturing at reduced cost and increased productivity. With optimized, scalable processes, Type 2 Drug Master Files, and cGMP products, we have enabled therapeutic programs to traverse their path to clinical translation in under 1 year.
RoosterBio is driven by our client's success and creating a world where safe and effective regenerative medicines are rapidly developed and widely available on a global scale.
FEATURED ARTICLES
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Modern solutions are continuing to be developed to help those working in biologics overcome historic Exosomes / Extracellular Vesicles challenges.
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While more biotech companies are entering the market, advanced therapy startups can still benefit greatly from product and service options that help address challenges in the MSC or EV / exosome space.
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Take a look at important information and data from PubMed publications regarding cancer and fibrosis research and as well as learning about MSCs & their EVs/Exosomes.
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Gain insight into the importance of scalability for future clinical products made from extracellular vesicles, the quality of peer-reviewed extracellular vesicle/exosome science, and more.
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Explore the highlights of ASGCT-2023 and how RoosterBio uniquely contributed knowledge related to EVs and/or exosomes that benefitted those in attendance.
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A newly developed genetic engineering medium is fueling the development of cell- and extracellular vesicle-based therapies.
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Did you know that mitochondrial transplantation therapies have already been tried in humans and that there’s a firm rationale for this biomedical technology?
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Explore overcoming the challenges of MSC and EV Production and how bone marrow-MSC EVs with anti-inflammatory activity are being used to treat retinal degeneration and traumatic brain injuries.
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The need for a single platform that assists EV manufacturers in meeting necessary criteria is driving technology innovations, including work on structured fixed-bed bioreactors.
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Knowing the MISEV characterization guideline will allow your researchers to report EV studies in a uniform, transparent manner allowing for data comparison and reproducibility across different labs.
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Find out how EV analytics will help you analyze your process and define your product, while learning about EV manufacturing strategies and MISEV guidelines.
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Explore the tricky challenge of gene transfer into primary cells, along with the impact of genetic engineering on the next wave of cell and exosomes advanced therapies and other developments.
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Explore ways to make establishing MSCs and Exosomes within programs, scaling them for product and process development, and translating them into the clinic easier.
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Learn about a novel method to obtain unique HUCPVs and how premium quality hUC-MSCs drive innovative translational research.
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Learn about one path forward to navigate the pitfalls with mRNA transfection and a medium to assist in lentivirus-mediated transduction of human mesenchymal stromal/stem cells (hMSCs).
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Learn about new data that highlights exciting uses for future immunotherapy studies.
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Learn more about plausible benefits of AAV’s use in concert with hMSCs, and how a complete genetic engineering medium was expanded beyond lentivirus.
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Learn how to incorporate standardized cell banks & right-scaled processes into your experimental design for rapid implementation & robust, reproducible results.
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Learn more about a system that fuels the rapid commercialization of scalable regenerative cures.
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Explore some of the questions and theories behind why, after compelling pre-clinical and human safety data, MSC therapeutics are not progressing faster.
CONTACT INFORMATION
RoosterBio
5295 Westview Drive Suite 275
Frederick, MD 21703
UNITED STATES
Phone: 240-831-4914
RESOURCES
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When MSCs are genome-edited, it will inevitably be done with cell therapy in mind and should involve complementary breakthroughs to scale up and industrialize gene delivery.
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Available in multiple tissues origins and from multiple donors, RoosterBio’s human mesenchymal stem/stromal cells (hMSCs) are sourced under strict guidelines, manufactured with highly standardized processes, and supported by 1st in class characterization.
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Eliminate media exchanges with RoosterNourish™ hMSC expansion medium and RoosterReplenish™ in-process bioreactor feed.
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Standardize the production of exosomes/extracellular vesicles with a translation-friendly, scalable system designed to streamline your process from cell-expansion to optimized EV collection yields.
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RoosterGEM™ is a complete genetic engineering medium that allows researchers and product developers to confidently engineer their therapeutic product with simplified end-to-end processes.
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RoosterBio’s Cell & Media Kits allow you to economically screen multiple hMSC donors or tissues and rapidly evaluate RoosterBio’s media exchange-free system.
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RoosterBio’s CliniControl™ products include human mesenchymal stem/stromal cells, bioprocess expansion media, and exosome/extracellular vesicle production media manufactured in compliance with cGMPs and supported by U.S. FDA Type II Master Files.
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The path to IND approval for cell-based therapies can be challenging and time-consuming with strict regulatory requirements.
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Advanced therapy programs are complex arrays of upstream and downstream processes that must reliably work together to produce consistent products worthy of clinical use.
BROCHURES
- Ready-To-Use Exosomes That Streamline R&D
- RoosterGEM™ - A Complete Genetic Engineering Medium
- RoosterVial™ MSCs
- RoosterNourish™ Mesenchymal Stromal Cell (MSC) Expansion Media
- RoosterCollect™ Exosome/Extracellular Vesicle Production
- RoosterReplenish™ hMSC Bioreactor Feed
- RoosterBio Process Development Services
- RoosterCollect EV Pro™ - Extracellular Vesicle (EV) Production